HOFFMAN-LA ROCHE INC -- DALMANE-30MG;FLURAZEPAM HYDROCHLORIDE -- 6505-00-400-7294
===================== Product Identification =====================
Product ID:DALMANE-30MG;FLURAZEPAM HYDROCHLORIDE
MSDS Date:10/31/1985
FSC:6505
NIIN:00-400-7294
MSDS Number: BTHMR
=== Responsible Party ===
Company Name:HOFFMAN-LA ROCHE INC
Address:340 KINGSLAND ST
City:NUTLEY
State:NJ
ZIP:07110-1141
Country:US
Info Phone Num:201-235-2323
Emergency Phone Num:201-235-2323
CAGE:04493
=== Contractor Identification ===
Company Name:HOFFMAN-LA ROCHE INC
Address:340 KINGSLAND ST
City:NUTLEY
State:NJ
ZIP:07110-1141
Country:US
Phone:201-235-2323
CAGE:04493
============= Composition/Information on Ingredients =============
Ingred Name:FLURAZEPAM HYDROCHLORIDE,30 MG PER TABLET
CAS:1172-18-5
RTECS #:DF0875000
Other REC Limits:NONE RECOMMENDED
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL LD50 (RABBIT) IS 368MG/KG/5DAYS
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:INGEST/INHAL:MAY CAUSE CNS DEPRESSION.
Explanation of Carcinogenicity:THERE ARE NO INGREDIENTS ABOVE 0.1%
WHICH ARE IDENTIFIED AS CARCINOGENS BY NTP,IARC OR OSHA.
Effects of Overexposure:CNS
DEPRESSION:DIZZINESS,DROWSINESS,LIGHT-HEADEDNESS,TENDANCY TO
FALL,IRRITABILITY,APPREHENSION,WEAKNESS,GENERALIZED
PAIN,HEADACHE,FLUSHING,PERSPIRING,HYPERSALIVATION,LOSS OF
APPETITE,MOOD CHANGES,VIS UAL EFFECTS,HALUCINATIONS.
Medical Cond Aggravated by Exposure:PERSONS WITH PRE-EXISTING KIDNEY OR
LIVER AILMENTS MAY BE AT INCREASED RISK FROM EXPOSURE.
======================= First Aid Measures =======================
First Aid:SKIN:WASH WITH SOAP AND WATER.EYES:FLUSH WITH WATER FOR 15
MINUTES.INHAL:REMOVE TO FRESH AIR.TREAT AS IF INGESTED.INGEST:GET
PROMPT QUALIFIED MEDICAL ATTENTION.USE SUPPORTIVE MEASURES;USE
IMMEDIATE GA STRIC LAVAGE;GIVE INTRAVENOUS FLUIDS;MAINTAIN AIRWAY.
===================== Fire Fighting Measures =====================
Flash Point:NONE
Extinguishing Media:WATER SPRAY,DRY CHEMICAL,CARBON DIOXIDE,FOAM.AS
APPROPRIATE FOR SURROUNDING FIRE.
Fire Fighting Procedures:USE A SELF-CONTAINED BREATHING APPARATUS AND
FULL PROTECTIVE EQUIPMENT.COOL FIRE EXPOSED CONTAINERS WITH WATER
SPRAY.
Unusual Fire/Explosion Hazard:AS WITH ANY DUST THERE IS AN EXPLOSION
HAZARD.BOND CONTAINERS WHEN TRANSFERRING MATERIALS.
================== Accidental Release Measures ==================
Spill Release Procedures:TRANSFER TO A PROPERLY LABELED CONTAINER.
Neutralizing Agent:NONE
====================== Handling and Storage ======================
Handling and Storage Precautions:HANDLE THIS SUBSTANCE IN THE MANNER
PRESCRIBED BY SCHEDULE IV OF THE CONTROLLED SUBSTANCES ACT.
Other Precautions:NONE
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WHERE ENVIRONMENTAL CONTROLS ARE LACKING OR IN
ENCLOSED SPACES USE A NIOSH RESPIRATOR FOR DUST.
Ventilation:LOCAL VENTILATION AT THE WORKSITE;MECHANICAL(GENERAL)
VENTILATION TO MAINTAIN TLV/PEL.
Protective Gloves:IF NEEDED
Eye Protection:SAFETY GLASSES
Other Protective Equipment:LAB COAT.PROVIDE A LOCAL EYE WASH STATION.
Work Hygienic Practices:FOLLOW RECOMMENDATIONS AS SET FORTH IN SCHEDULE
IV OF THE CONTROLLED SUBSTANCES ACT.
Supplemental Safety and Health
NDC#0140-0066-27.
================== Physical/Chemical Properties ==================
HCC:T4
Melt/Freeze Pt:M.P/F.P Text:406F DECOMP
Decomp Temp:Decomp Text:406F,208C
Solubility in Water:APPRECIABLE
Appearance and Odor:CAPSULES;OFF-WHITE TO YELLOW;ODORLESS TO SLIGHT
ODOR
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
ACIDS(<3)ES(>7).
Stability Condition to Avoid:LIGHT
Hazardous Decomposition Products:IN SOLUTION WITH ACIDS AND BASES,THIS
ITEM UNDERGOES HYDROLYSIS TO BENZOPHENONE.
==================== Disposal Considerations ====================
Waste Disposal Methods:DESTROY THIS MATERIAL IN A MANNER PRESCRIBED BY
SCHEDULE IV OF THE CONTROLLED SUBSTANCES ACT.
======================================================================
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.