UNITED STATES PHARMACOPEIAL CONVENTION INC -- DIHYDROERGOTAMINE MESYLATE -- 6505-00F036918
===================== Product Identification =====================
Product ID:DIHYDROERGOTAMINE MESYLATE
MSDS Date:02/02/1989
FSC:6505
NIIN:00F036918
MSDS Number: BVSQW
=== Responsible Party ===
Company Name:UNITED STATES PHARMACOPEIAL CONVENTION INC
Address:12601 TWINBROOK PKWY
City:ROCKVILLE
State:MD
ZIP:20852-1717
Country:US
Info Phone Num:301-881-0666
Emergency Phone Num:301-881-0666
Preparer's Name:WILLIAM M HELLER
CAGE:14128
=== Contractor Identification ===
Company Name:UNITED STATES PHARMACOPEIAL CONVENTION INC
Address:12601 TWINBROOK PKWY
Box:City:ROCKVILLE
State:MD
ZIP:20852-1717
Country:US
Phone:301-881-0666
CAGE:14128
============= Composition/Information on Ingredients =============
Ingred Name:MESYLATE *94-3*
CAS:6190-39-2
RTECS #:KE7920000
Ingred Name:DIHYDROERGOTAMINE *94-3*
CAS:511-12-6
RTECS #:II3675000
===================== Hazards Identification =====================
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:POSSIBLE ALLERGIC REACTION TO DUST IF
INHALED/INGESTED/CONTACT W/SKIN. EYE/SKIN/RESPIRATORY TRACT
IRRITATION. POSSIBLE HYPERSENSITIZATION. IRRITATING TO MUCOUS
MEMBRANES & RESPIRATORY TRACT. DON'T USE DURING PREGNANCY. MAY BE
HYPERSENSITIVE TO THIS MATERIAL IF HYPERSENSITIVE TO OTHER ERGOT
DERIVATIVES.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION, NAUSEA, VOMITING, HEADACHE,
DIARRHEA, THIRST, COLDNESS OF SKIN, PRURITUS, WEAK PULSE, NUMBNESS,
TINGLING OF EXTREMITIES, CONFUSION.
Medical Cond Aggravated by Exposure:HYPERSENSITIVITY TO MATERIAL,
CORONARY ARTERY DISEASE, RENAL IMPAIRMENT
======================= First Aid Measures =======================
First Aid:INHALATION: REMOVE TO FRESH AIR. GIVE CPR/OXYGEN IF NEEDED.
EYES/SKIN: FLUSH W/COPIOUS QUANTITIES OF WATER. INGESTION: FLUSH
OUT MOUTH W/WATER. TREATMENT OF ACUTE POISONING IS SYMPTOMATIC.
EMPTY STOMA CH BY ASPIRATION/LAVAGE. AMYL NITRATE INHALATIONS
HELPFUL. CONTROL NAUSEA/VOMITING BY INTRAMUSCULAR INJECTION OF
25-50MG CHLOROPROMAZINE/COMPARABLE DOSE OF RELATED PHENOTHIAZINE.
(SUPP)
===================== Fire Fighting Measures =====================
Extinguishing Media:WATER SPRAY, DRY CHEMICAL, CO2, FOAM AS APPROPRIATE
FOR SURROUNDING FIRE/MATERIALS.
Fire Fighting Procedures:EVACUATE AREA. WEAR SELF CONTAINED BREATHING
APPARATUS & PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:MATERIAL IS ASSUMED TO BE COMBUSTIBLE. AS
W/ALL DRY POWDERS IT'S ADVISABLE TO GROUND MECHANICAL EQUIPMENT IN
CONTACT W/DRY MATERIAL TO DISSIPATE STATIC.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR APPROVED RESPIRATOR & CHEMICALLY
COMPATIBLE GLOVES. VACUUM/SWEEP UP. AVOID DUST. PLACE MATERIAL IN
APPROPRIATE CONTAINER FOR WASTE DISPOSAL. VENTILATE AREA & WASH
SITE.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN TIGHT CONTAINER. SHOULD BE
HANDLED/STORED PER LABEL/OTHER INSTRUCTIONS TO ENSURE PRODUCT
INTEGRITY. USE W/ADEQUATE VENTILATION.
Other Precautions:AVOID CONTACT W/EYES, SKIN/CLOTHING. AVOID BREATHING
DUST/MIST/FUMES/VAPORS. USE W/ADEQUATE DUST CONROL. DON'T PERMIT
EATING/DRINKING/SMOKING NEAR MATERIAL.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WEAR NIOSH APPROVED RESPIRATOR.
Ventilation:ADEQUATE. LOCAL EXHAUST/MECHANICAL (GENERAL): RECOMMENDED.
Protective Gloves:RUBBER
Eye Protection:SAFETY GOGGLES
Other Protective Equipment:APPROPRIATE LABORATORY APPAREL
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE. WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
INDIVIDUALS WORKING W/CHEMICALS SHOULD CONSIDER ALL CHEMICALS TO BE
POTENTIALLY HAZARDOUS EVEN IF THEIR INDIVIDUAL HAZARDS MAY BE
UNCHARACTERIZED/UNKNOWN. FIRST AID CONT'D: HYPERSENSITIVITY
REACTIONS MUST RECEIVE IMMEDIATE MEDICAL ATTENTION. OBTAIN MEDICAL
ATTENTION IN ALL CASES.
================== Physical/Chemical Properties ==================
Solubility in Water:SLIGHT
Appearance and Odor:WHITE TO SLIGHTLY YELLOWISH POWDER/OFF-WHITE TO
FAINTLY RED POWDER W/FAINT ODOR
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:HEAT
Hazardous Decomposition Products:TOXIC FUMES, SULFUR OXIDES, NITROGEN
OXIDES.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.