Safety (MSDS) data for hydrochlorothiazide

Safety (MSDS) data for hydrochlorothiazide

Hazard: harmful


    Synonyms: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, HCTZ, HCZ, hydril, hydrodiuril, dyazide, hydrosaluric, hypothaizide, hypothiazid, NCI-C55925, nefrix, oretic, aquarills, vetidrex, aquarius, ivaugan, chlorosulphadil, cidrex, panurin, neoflumen, vetidrex, esidrex, neocodema, dichlorosal, numerous other trade names
    Use: diuretic
    Molecular formula: C7H8ClN3O4S2
    CAS No: 58-93-5
    EINECS No:

Physical data

    Appearance: white crystalline powder
    Melting point: 273 - 275 C
    Boiling point:
    Vapour density:
    Vapour pressure:
    Density (g cm-3):
    Flash point:
    Explosion limits:
    Autoignition temperature:
    Water solubility: negligible


    Stable. Incompatible with strong oxidizing agents.


    Harmful if swallowed. May cause sensitisation. Skin, eye and respiratory irritant.

    Toxicity data
    (The meaning of any toxicological abbreviations which appear in this section is given here.)
    ORL-MUS LD50 3080 mg kg-1
    IPR-MUS LD50 578 mg kg-1
    IVN-MUS LD50 590 mg kg-1
    IPR-RAT LD50 234 mg kg-1

    Risk phrases
    (The meaning of any risk phrases which appear in this section is given here.)
    R22 R42 R43.

Transport information

    (The meaning of any UN hazard codes which appear in this section is given here.)
    Non-hazardous for air, sea and road freight.

Personal protection

    Safety glasses.

    Safety phrases
    (The meaning of any safety phrases which appear in this section is given here.)

[Return to Physical & Theoretical Chemistry Lab. Safety home page.]

This information was last updated on October 13, 2003. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.