General

Synonyms: 2-chloro-10-(3-dimethylaminopropyl)phenothiazine monohydrochloride, thorazine, neurazine, propaphen, promacid, sonazine, torazina, chloracetil, numerous other trade names
Use: anti-emetic, antipsychotic drug
Molecular formula: C₁₇H₁₉ClN₂S.HCl
CAS No: 69-09-0
EC No:

Physical data

Appearance: creamy white crystalline powder
Melting point: ca. 193 C (decomposes)
Boiling point:
Vapour density:
Vapour pressure:
Density (g cm^-3):
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility: moderate
 

Stability

Stable. Combustible. Incompatible with strong oxidizing agents. Air and light sesnsitive.

Toxicology

Poison. Experimental teratogen. May cause reproductive defects. Irritant. May lead to dermatitis in sensitized individuals.

Toxicity data
(The meaning of any abbreviations which appear in this section is given here.)
IPR-RAT LD50 62 mg kg^-1
SCU-RAT LD50 140 mg kg^-1
IVN-RAT LD50 25 mg kg^-1
ORL-RAT LD50 145 mg kg^-1
ORL-WMN TDLO 6 mg kg^-1
IVN-RBT LD50 5 mg kg^-1

Risk phrases
(The meaning of any risk phrases which appear in this section is given here.)
R36 R37 R38 R47.

Transport information

(The meaning of any UN hazard codes which appear in this section is given here.)
UN No 2811. Hazard class 6.1. Packing group III.

Personal protection

Safety glasses, good ventilation. Gloves.

Safety phrases
(The meaning of any safety phrases which appear in this section is given here.)

[Return to Physical & Theoretical Chemistry Lab. Safety home page.]

This information was last updated on March 17, 2005. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.