Chloromeridin

UPJOHN CO -- COLESTID GRANULES -- 6505-00D020066
=====================  Product Identification  =====================

Product ID:COLESTID GRANULES
MSDS Date:01/01/1994
FSC:6505
NIIN:00D020066
MSDS Number: BVGXP
=== Responsible Party ===
Company Name:UPJOHN CO
Address:7000 PORTAGE ROAD
City:KALAMAZOO
State:MI
ZIP:49001
Country:US
Info Phone Num:616-323-7555 (8:00 AM - 4:30 PM)
Emergency Phone Num:616-323-6722 (24 HOURS)
CAGE:EO390
=== Contractor Identification ===
Company Name:PHARMACIA & UPJOHN
Address:7171 PORTAGE RD
Box:City:KALAMAZOO
State:MI
ZIP:49001-0199
Country:US
Phone:616-833-5122/616-833-7555
CAGE:93703
Company Name:UPJOHN CO
Address:7000 PORTAGE ROAD
Box:City:KALAMAZOO
State:MI
ZIP:49001
Country:US
Phone:616-323-7555 (8:00 AM - 4:30 PM)
CAGE:EO390

=============  Composition/Information on Ingredients  =============

Ingred Name:SILICA GEL
CAS:112945-52-5
RTECS #:VV7310000
Fraction by Wt: 0.2% %
Other REC Limits:NONE RECOMMENDED
OSHA PEL:6 MG/M3
ACGIH TLV:10 MG/M3

Ingred Name:COLESTIPOL HYDROCHLORIDE
CAS:37296-80-3
Fraction by Wt: 99.8% %
Other REC Limits:NONE RECOMMENDED

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:ORAL LD50 (RAT): > 1000 MG/KG
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:ADVERSE EFFECTS TO PERSONS HANDLING
    THIS MATERIAL IN CLINICAL SETTING ARE NOT ANTICIPATED. OCULAR
    EXPOSURE MAY CAUSE SEVERE EYE IRRITATION ANS CORNEAL ABRASION.
    INGESTION MAY CAUSE CONSITPATION, ABDOM INAL DISCOMFORT, NAUSEA,
    VOMITING, DIARRHEA, HYPERSENSITIVITY.
Explanation of Carcinogenicity:THIS COMPOUND CONTAINS NO INGREDIENTS AT
    CONCENTRATIONS OF 0.1% OR GREATER THAT ARE CARCINOGENS OR SUSPECT
    CARCINOGENS.
Effects of Overexposure:EYE IRRITATION, CONSTIPATION, ABDOMINAL CRAMPS,
    NAUSEA, VOMITING, DIARRHEA, HYPERSENSITIVITY.
Medical Cond Aggravated by Exposure:CONTRAINDICATED IN PERSONS WITH
    KNOWN HYPERSENSITIVITY TO COLESTIPOL HYDROCHLORIDE, HYPOTHYROIDISM,
    DIABETES MELLITUS, NEPHROTIC SYNDROME, DYSPROTEINEMIAS AND
    OBSTRUCTIVE LIVER DISEASE.

=======================  First Aid Measures  =======================

First Aid:EYES: FLUSH WITH WATER FOR 15 MINUTES WHILE HOLDING EYELIDS
    OPEN. GET MEDICAL ATTENTION. SKIN: REMOVE CONTAMINATED CLOTHING.
    WASH WITH SOAP AND WATER. IF IRRITATION PERSISTS, GET MEDICAL
    ATTENTION. IN HALATION: REMOVE TO FRESH AIR. RESTORE BREATHING. GET
    MEDICAL ATTENTION. INGESTION: DO NOT INDUCE VOMITING. GET MEDICAL
    ATTENTION.

=====================  Fire Fighting Measures  =====================

Flash Point:NONFLAMMABLE
Lower Limits:NOT GIVEN
Upper Limits:NOT GIVEN
Extinguishing Media:WATER, DRY CHEMICAL, CARBON DIOXIDE
Fire Fighting Procedures:FIRE FIGHTERS SHOULD USE NIOSH APPROVED SCBA &
    FULL PROTECTIVE EQUIPMENT WHEN FIGHTING CHEMICAL FIRE.
Unusual Fire/Explosion Hazard:NONE SPECIFIED BY MANUFACTURER.

==================  Accidental Release Measures  ==================

Spill Release Procedures:EVACUATE AREA. WEAR PROPER PERSONAL PROTECTIVE
    EQUIPMENT. CONTAIN SPILL. KEEP OUT OT DRAINS; PREVENT ENTRY TO
    SURFACE WATER, GROUNDWATER AND SOIL. SMALL SPILLS SHOULD BE
    ABSORBED WITH PAPER TOWELS. LA RGE SPILLS MAY BE VACUUMED OR
    SCOOPED UP.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

======================	Handling and Storage  ======================

Handling and Storage Precautions:AVOID CONTACT WITH SKIN ,EYES AND
    CLOTHING. WASH THOROUGHLY AFTER HANDLING. STORE IN A COOL, DRY
    PLACE AND PROTECT FROM LIGHT.
Other Precautions:AVOID SKIN CONTACT. LAUNDER CONTAMINATED CLOTHING
    BEFORE REUSE. KEEP OUT OF REACH OF CHILDREN.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NOT NORMALLY REQUIRED.
Ventilation:LOCAL EXHAUST AND MECHANICAL (GENERAL) VENTILATION TO
    MAINTAIN EXPOSURE LEVELS.
Protective Gloves:RUBBER
Eye Protection:NOT REQUIRED
Other Protective Equipment:AN EMERGENCY EYE WASH STATION AND SHOWER
    SHOULD BE AVAILABLE.
Work Hygienic Practices:WASH WITH SOAP AND WATER AFTER HANDLING PRODUCT
    AND BEFORE EATING DRINKING OR SMOKING.
Supplemental Safety and Health
NONE SPECIFIED BY MANUFACTURER.

==================  Physical/Chemical Properties  ==================

HCC:N1
Boiling Pt:B.P. Text:NOT GIVEN
Melt/Freeze Pt:M.P/F.P Text:NOT GIVEN
Vapor Pres:NOT GIVEN
Vapor Density:NOT GIVEN
Spec Gravity:NOT GIVEN
Evaporation Rate & Reference:NOT GIVEN
Solubility in Water:INSOLUBLE
Appearance and Odor:LIGHT YELLOW GRANULES IN 5-G FOIL PACKETS, 330-G
    AND 500-G BOTTLES, NO ODOR

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
NONE SPECIFIED BY MANUFACTURER.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:CARBON MONOXIDE, CARBON DIOXIDE,
    HYDROCHLORIC ACID FUMES

====================  Disposal Considerations  ====================

Waste Disposal Methods:PREVENT WASTE FROM CONTAMINATING SURROUNDING
    ENVIRONMENT. DISCARD ANY PRODUCT, RESIDUE, DISPOSAL CONTAINER OR
    LINER IN ACCORDANCE WITH ALL FEDERAL, STATE AND LOCAL REGULATIONS.

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