LYPHOMED INC., DIV OF FUJISAWA -- CEPHALOTHIN SODIUM FOR INJECTION ======================================================= MSDS Safety Information ======================================================= FSC: 6505 NIIN: 01-308-9433 MSDS Date: 10/07/1992 MSDS Num: BQQQT Product ID: CEPHALOTHIN SODIUM FOR INJECTION MFN: 01 Responsible Party Cage: JO920 Name: LYPHOMED INC., DIV OF FUJISAWA USA INC Address: 3 PARKWAY NORTH, PARKWAY NORTH CENTER City: DEERFIELD IL 60015-2548 Info Phone Number: 708-317-0800/8952 Emergency Phone Number: 800-888-7704 Preparer's Name: GREGORY KOLAR Review Ind: Y Published: Y ======================================================= Contractor Summary ======================================================= Cage: 39832 Name: FUJISAWA USA, INC Address: 3 PKY N City: DEERFIELD IL 60015-2548 Phone: 847-317-1256 Cage: JO920 Name: LYPHOMED INC., DIV OF FUJISAWA USA INC Address: 3 PARKWAY NORTH, PARKWAY NORTH CENTER City: DEERFIELD IL 60015-2548 Phone: 708-317-0800/8952 ======================================================= Item Description Information ======================================================= Item Manager: S9M Item Name: CEPHALOTHIN SODIUM FOR INJECTION,USP Unit of Issue: PG Quantitative Expression: 00000000025EA UI Container Qty: 1 Type of Container: PACKAGE ======================================================= Ingredients ======================================================= Cas: 58-71-9 RTECS #: XI0383000 Name: CEPHALOTHIN SODIUM Other REC Limits: NONE RECOMMENDED OSHA PEL: NOT ESTABLISHED ACGIH TLV: NOT ESTABLISHED ------------------------------ Cas: 144-55-8 RTECS #: VZ0950000 Name: SODIUM BICARBONATE Other REC Limits: NONE RECOMMENDED OSHA PEL: NOT ESTABLISHED ACGIH TLV: NOT ESTABLISHED ======================================================= Health Hazards Data ======================================================= LD50 LC50 Mixture: LD50 (IV RAT) 4000 MG/KG Route Of Entry Inds - Inhalation: NO Skin: NO Ingestion: NO Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO Effects of Exposure: ACUTE- THIS PRODUCT IS INTENDED FOR THERAPUTIC USE ONLY WHEN PRESCRIBED BY A PHYSICIAN. OCCUPATIONAL EXPOSURE HAS NOT BEEN FULLY INVESTIGATED. EYE, SKIN AND RESPIRATORY IRRITATION MAY OCCUR. CHRONIC- UNKNOWN. Signs And Symptions Of Overexposure: EYE, SKIN AND RESPIRATORY IRRITATION MAY OCCUR. Medical Cond Aggravated By Exposure: NOT KNOWN First Aid: GET MEDICAL ATTENTION. EYE/SKIN:FLUSH WITH WATER FOR 15 MINUTES. HOLD EYELIDS OPEN. REMOVE CONTAMINATED CLOTHING. INHALED:REMOVE TO FRESH AIR & PROVIDE OXYGEN/CPR IF NEEDED. ORAL:FLUSH MOUTH OUT WITH WATER IMMEDIATELY. CALL A PHYSICIAN. ======================================================= Handling and Disposal ======================================================= Spill Release Procedures: WEAR RECOMMENDED PERSONAL PROTECTIVE EQUIPMENT. USE ABSORBENT TOWELS TO CLEAN-UP SPILL. WIPE SURFACES CLEAN AND WASH WITH SOAP AND WATER. Waste Disposal Methods: DISPOSE OF IN ACCORDANCE WITH ALL LOCAL, STATE AND FEDERAL REGULATIONS. Handling And Storage Precautions: STORE AT ROOM TEMPERATURES. AVOID EXCESSIVE LIGHT AND HEAT. Other Precautions: AS A GENERAL RULE, WHEN HANDLING PHARMACEUTICAL PRODUCTS AVOID ALL CONTACT AND INHALATION OF DUST, FUME, MISTS AND/OR VAPORS ASSOCIATED WITH THE PRODUCT. KEEP OUT OF REACH OF CHILDREN. ======================================================= Fire and Explosion Hazard Information ======================================================= Flash Point Text: COMBUSTIBLE PWDR Extinguishing Media: WATER SPRAY, CO2, FOAM/DRY CHEMICAL FOR SURROUNDING FIRE. WATER SPRAY MAY BE USED TO KEEP FIRE EXPOSED CONTAINERS COOL. Fire Fighting Procedures: WEAR NIOSH-APPROVED SELF-CONTAINED BREATHING APPARATUS OR STAY UPWIND AND DO NOT BREATHE FUMES OR DUST. MOVE CONTAINERS AWAY IF POSSIBLE. Unusual Fire/Explosion Hazard: NOT KNOWN ======================================================= Control Measures ======================================================= Respiratory Protection: WITH SATISFACTORY VENTILATION, RESPIRATORY PROTECTION NOT USUALLY REQUIRED. Ventilation: GENERAL ROOM VENTILATION IS USUALLY SATISFACTORY. USE LOCAL EXHAUST VENTILATION WHEN NECESSARY. Protective Gloves: DISPOSABLE LATEX GLOVES RECOMMENDED Eye Protection: SAFETY GOGGLES/GLASSES RECOMMENDED Other Protective Equipment: EYE WASH STATION, QUICK DRENCH SHOWER AND DISPOSABLE GARMENTS IF DIRECT SKIN CONTACT IS ANTICIPATED. Work Hygienic Practices: OBSERVE GOOD PERSONAL HYGIENE PRACTICES AND RECOMMENDED PROCEDURES. ======================================================= Physical/Chemical Properties ======================================================= HCC: N1 Spec Gravity: NOT KNOWN PH: 6- 8.5 Evaporation Rate & Reference: NOT RELEVANT Solubility in Water: FREELY SOLUBLE Appearance and Odor: WHITE TO OFF-WHITE POWDER, ODORLESS Corrosion Rate: UNKNOWN ======================================================= Reactivity Data ======================================================= Stability Indicator: YES Stability Condition To Avoid: EXCESSIVE HEAT AND LIGHT MAY CAUSE DECOMPOSITION. Materials To Avoid: NOT KNOWN Hazardous Decomposition Products: WHEN HEATED TO DECOMPOSITION, IT EMITS TOXIC FUMES OF NOX AND SOX. Hazardous Polymerization Indicator: NO ======================================================= Toxicological Information ======================================================= ======================================================= Ecological Information ======================================================= ======================================================= MSDS Transport Information ======================================================= ======================================================= Regulatory Information ======================================================= ======================================================= Other Information ======================================================= ======================================================= Transportation Information ======================================================= Responsible Party Cage: JO920 Trans ID NO: 124123 Product ID: CEPHALOTHIN SODIUM FOR INJECTION MSDS Prepared Date: 10/07/1992 Review Date: 05/21/1993 MFN: 1 Net Unit Weight: 1.70 LBS Multiple KIT Number: 0 Review IND: Y Unit Of Issue: PG Container QTY: 1 Type Of Container: PACKAGE ======================================================= Detail DOT Information ======================================================= DOT PSN Code: ZZZ DOT Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION ======================================================= Detail IMO Information ======================================================= IMO PSN Code: ZZZ IMO Proper Shipping Name: NOT REGULATED FOR THIS MODE OF TRANSPORTATION ======================================================= Detail IATA Information ======================================================= IATA PSN Code: ZZZ IATA Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION ======================================================= Detail AFI Information ======================================================= AFI PSN Code: ZZZ AFI Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION ======================================================= HAZCOM Label ======================================================= Product ID: CEPHALOTHIN SODIUM FOR INJECTION Cage: JO920 Assigned IND: Y Company Name: LYPHOMED INC., DIV OF FUJISAWA USA INC Street: 3 PARKWAY NORTH, PARKWAY NORTH CENTER City: DEERFIELD IL Zipcode: 60015-2548 Health Emergency Phone: 800-888-7704 Date Of Label Review: 05/21/1993 Status Code: C Label Date: 05/21/1993 Origination Code: Z Eye Protection IND: YES Signal Word: CAUTION Health Hazard: Slight Contact Hazard: Slight Fire Hazard: Slight Reactivity Hazard: None Hazard And Precautions: ACUTE- THIS PRODUCT IS INTENDED FOR THERAPUTIC USE ONLY WHEN PRESCRIBED BY A PHYSICIAN. OCCUPATIONAL EXPOSURE HAS NOT BEEN FULLY INVESTIGATED. EYE, SKIN AND RESPIRATORY IRRITATION MAY OCCUR. CHRONIC- UNKNOWN. STORE AT ROOM TEMPERATURES. INCASE OF SPILL: WEAR RECOMMENDED PERSONAL PROTECTIVE EQUIPMENT. USE ABSORBENT TOWELS TO CLEAN-UP SPILL. WIPE SURFACES CLEAN AND WASH WITH SOAP & WATER. FIRST AID- GET MEDICAL ATTENTION. EYE/SKIN:FLUSH WITH WATER FOR 15 MINUTES. HOLD EYELIDSOPEN. REMOVE CONTAMINATED CLOTHING. INHALED:REMOVE TO FRESH AIR & PROVIDE OXYGEN/CPR IF NEEDED. ORAL:FLUSH MOUTH OUT WITH WATER IMMEDIATELY. CALL DOCTOR. ======================================================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever expressly or implied warrants, states, or intends said information to have any application, use or viability by or to any person or persons outside the Department of Defense nor any person or persons contracting with any instrumentality of the United States of America and disclaims all liability for such use. Any person utilizing this instruction who is not a military or civilian employee of the United States of America should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation regardless of similarity to a corresponding Department of Defense or other government situation.