Safety (MSDS) data for azathioprine

Safety (MSDS) data for azathioprine

Hazard: harmful


    Synonyms: 6-((1-methyl-4-nitroimidazol-5-yl)thio)purine, imuran, ccucol, bw 57-322, azatioprin, cytostatics, methylnitroimidazolylmercaptopurine, imurek, imurel, rorasul
    Use: antitumor agent
    Molecular formula: C9H7N7O2S
    CAS No: 446-86-6
    EINECS No:

Physical data

    Appearance: pale yellow crystalline powder
    Melting point: ca. 244 C (decomposes)
    Boiling point:
    Vapour density:
    Vapour pressure:
    Density (g cm-3):
    Flash point:
    Explosion limits:
    Autoignition temperature:
    Water solubility: negligible


    Stable. Incompatible with strong oxidizing agents, strong bases.


    Harmful if swallowed, inhaled or absorbed through the skin. Experimental carcinogen. IARC human carcinogen.

    Toxicity data
    (The meaning of any toxicological abbreviations which appear in this section is given here.)
    ORL-RAT LD50 535 mg kg-1
    UNR-CHD TDLO 2.5 mg kg-1 D-I
    IPR-RAT LD50 300 mg kg-1
    ORL-MUS LD50 1389 mg kg-1
    SCU-MUS LD50 350 mg kg-1

    Risk phrases
    (The meaning of any risk phrases which appear in this section is given here.)
    R20 R21 R22 R45.

Transport information

    (The meaning of any UN hazard codes which appear in this section is given here.)

Personal protection

    Safety glasses, gloves, good ventilation. Handle as a carcinogen.

    Safety phrases
    (The meaning of any safety phrases which appear in this section is given here.)

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This information was last updated on February 22, 2005. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.