General
Synonyms: 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid,
isoretinoin, neovitamin A acid, 13-RA, 13-cis-retinoic acid, RO-4-3780,
13-cis-vitamin A acid, accutane, retinoic acid 9z form
Use: antitumour agent, drug used in treatment of cystic acne
Molecular formula: C20H28O2
CAS No: 4759-48-2
EINECS No:
Physical data
Appearance: yellow to orange crystalline powder
Melting point: 189 - 190 C
Boiling point:
Vapour density:
Vapour pressure:
Density (g cm-3):
Flash point:
Explosion limits:
Autoignition temperature:
Water solubility: negligible
Stability
Stable, but probably air and light sensitive. Combustible. Incompatible
with strong oxidizing agents.
Toxicology
Not believed to be harmful in normal use.
Toxicity data
(The meaning of any toxicological abbreviations which
appear in this section is given
here.)
ORL-CHD TDLO 360 mg/kg/26w-i
ORL-MAN TDLO 750 mg/kg/12w-i
ORL-WMN TDLO 56 mg/kg/8w-i
Risk phrases
(The meaning of any risk phrases which appear in this section is
given
here.)
Transport information
(The meaning of any UN hazard codes which appear in this section
is given
here.)
Non-hazardous for air, sea and road freight.
Personal protection
[Return to Physical &
Theoretical Chemistry Lab. Safety home page.]
This information was last updated on October 27, 2004.
We have tried to make it as accurate and useful as possible, but
can take no responsibility for its use, misuse, or accuracy. We
have not verified this information, and cannot guarantee that it
is up-to-date.