Safety (MSDS) data for dl-methadone hydrochloride

Safety (MSDS) data for dl-methadone hydrochloride

Hazard: very toxic


    Synonyms: 6-dimethylamino-4,4-diphenyl-3-heptanone hydrochloride, 1,1-diphenyl-1-(2-dimethylaminopropyl)-2-butanone hydrochloride, 4,4-diphenyl-6-dimethylamino-3-heptanone hydrochloride, adanon, adanon hydrochloride, adolan, algidon, algolysin, amidon hydrochloride, butalgin, depridol, diaminon, diaminon hydrochloride, eptadone, fenadone, heptadon, heptadon hydrochloride, ketalgin, levadone, levothyl, mecodin, mephenon, metasedin, miadone, meheptan, phenadone, l-polamidon, symoron, tussal, tussol, westadone, further trade names
    Use: heroin substitute, narcotic, analgesic, detox maintenance drug
    Molecular formula: C21H28ClNO
    CAS No: 1095-90-5
    EINECS No:

Physical data

    Appearance: crystalline powder
    Melting point: 235 C
    Boiling point:
    Vapour density:
    Vapour pressure:
    Density (g cm-3):
    Flash point:
    Explosion limits:
    Autoignition temperature:
    Water solubility: moderate


    Stable. Incompatible with strong oxidizing agents.


    Experimental teratogen. Very toxic - lethal dose in humans is generally well below 1g. CNS depressant. May cause reproductive damage. May act as a hallucinogen. Severity of toxic effects may be enhanced by alcohol. May cause systemic effects. May interact with prescription and other drugs.

    Toxicity data
    (The meaning of any toxicological abbreviations which appear in this section is given here.)
    ORL-HMN LDLO 1.4 mg kg-1
    IVN-RAT LD50 9 mg kg-1
    IPN-MUS LD50 8 mg kg-1
    ORL-MUS LD50 124 mg kg-1

    Risk phrases
    (The meaning of any risk phrases which appear in this section is given here.)
    R26 R27 R28.

Transport information

    (The meaning of any UN hazard codes which appear in this section is given here.)

Personal protection

    Regulated drug in most countries. Wear gloves to prevent absorption through the skin. Ensure good ventilation.

    Safety phrases
    (The meaning of any safety phrases which appear in this section is given here.)

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This information was last updated on June 7, 2005. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.