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Exemestance Les marques, Exemestance Analogs

Exemestance Les marques melange

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  • Exemestance Formule chimique

    C20H24O2

    Exemestance RX lien

    http://www.rxlist.com/cgi/generic3/exemest.htm

    Exemestance FDA fiche

    Exemestance FDA

    Exemestance msds (fiche de securite des materiaux)

    Exemestance Synthese de reference

    Pfizer Canada Inc, numéro de brevet: 1277656

    Exemestance Poids moleculaire

    296.403 g/mol

    Exemestance Point de fusion

    155.13oC

    Exemestance H2O Solubilite

    Non-solubles

    Exemestance Etat

    Solid

    Exemestance LogP

    4.222

    Exemestance Formes pharmaceutiques

    Tablet

    Exemestance Indication

    Pour le traitement du cancer du sein avancé chez les femmes ménopausées dont la maladie a progressé après un traitement au tamoxifène.

    Exemestance Pharmacologie

    L'aromatase est une enzyme qui convertit les hormones d'oestrogène dans les glandes surrénales du corps. Les inhibiteurs de l'aromatase (IA) sont des médicaments qui réduisent les niveaux d'oestrogène en bloquant l'action de l'aromatase dans la surrénale glandes. L'AIS sélective (ISC) de réduire sélectivement des niveaux d'oestrogène sans interférer avec les niveaux des autres hormones stéroïdes qui sont produites par la glande surrénale. Médicaments de cette classe comprennent l'anastrozole (Arimidex ™), le létrozole (Femara ™) et l'exémestane (Aromasin ™).

    Exemestance Absorption

    42%

    Exemestance Toxicite

    Convulsions

    Exemestance Information pour les patients

    PATIENT INFORMATION

    If clinically advisable, patients receiving OxyContin� (oxycodone hydrochloride controlled-release) tablets or
    their caregivers should be given the following information by the physician, nurse, pharmacist, or caregiver:

    1. Patients should be aware that OxyContin� tablets contain oxycodone, which is a morphine-like substance.

    2. Patients should be advised that OxyContin� tablets were designed to work properly only if swallowed whole.
    OxyContin� tablets will release all their contents at once if broken, chewed, or crushed, resulting in a risk of
    fatal overdose.

    3. Patients should be advised to report episodes of breakthrough pain and adverse experiences occurring during
    therapy. Individualization of dosage is essential to make optimal use of this medication.

    4. Patients should be advised not to adjust the dose of OxyContin� without consulting the prescribing professional.

    5. Patients should be advised that OxyContin� may impair mental and/or physical ability required for the performance
    of potentially hazardous tasks (e.g., driving, operating heavy machinery).

    6. Patients should not combine OxyContin� with alcohol or other central nervous system depressants (sleep aids,
    tranquilizers) except by the orders of the prescribing physician, because dangerous additive effects may occur,
    resulting in serious injury or death.

    7. Women of childbearing potential who become, or are planning to become, pregnant should be advised to consult their
    physician regarding the effects of analgesics and other drug use during pregnancy on themselves and their unborn child.

    8. Patients should be advised that OxyContin� is a potential drug of abuse. They should protect it from theft, and it
    should never be given to anyone other than the individual for whom it was prescribed.

    9. Patients should be advised that they may pass empty matrix "ghosts" (tablets) via colostomy or in the stool, and that
    this is of no concern since the active medication has already been absorbed.

    10. Patients should be advised that if they have been receiving treatment with OxyContin� for more than a few weeks and
    cessation of therapy is indicated, it may be appropriate to taper the OxyContin� dose, rather than abruptly discontinue
    it, due to the risk of precipitating withdrawal symptoms. Their physician can provide a dose schedule to accomplish a
    gradual discontinuation of the medication.

    11. Patients should be instructed to keep OxyContin� in a secure place out of the reach of children. When OxyContin� is
    no longer needed, the unused tablets should be destroyed by flushing down the toilet.

    Exemestance Organismes affectes

    Les humains et autres mammifères