Sulfazin
Category
Sulfazin Brand names, Sulfazin Analogs
Sulfazin Brand Names Mixture
Sulfazin Chemical_Formula
C10H10N4O2S
Sulfazin RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Sulfazin fda sheet
Sulfazin msds (material safety sheet)
Sulfazin Synthesis Reference
No information avaliable
Sulfazin Molecular Weight
250.278 g/mol
Sulfazin Melting Point
No information avaliable
Sulfazin H2O Solubility
No information avaliable
Sulfazin State
Solid
Sulfazin LogP
1.883
Sulfazin Dosage Forms
Cream
Sulfazin Indication
For the treatment of rheumatic fever and meningococcal meningitis
Sulfazin Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfazin Absorption
No information avaliable
Sulfazin side effects and Toxicity
No information avaliable
Sulfazin Patient Information
No information avaliable
Sulfazin Organisms Affected
Enteric bacteria and other eubacteria
