Siplarol
Siplarol Brand names, Siplarol Analogs
Siplarol Brand Names Mixture
- No information avaliable
Siplarol Chemical_Formula
C23H25F3N2OS
Siplarol RX_link
No information avaliable
Siplarol fda sheet
Siplarol msds (material safety sheet)
Siplarol Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Siplarol Molecular Weight
434.519 g/mol
Siplarol Melting Point
No information avaliable
Siplarol H2O Solubility
0.000346 mg/ml
Siplarol State
Solid
Siplarol LogP
4.694
Siplarol Dosage Forms
Tablet; IM injection
Siplarol Indication
For use in the treatment of schizophrenia and depression
Siplarol Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Siplarol Absorption
Fairly slow and incomplete after oral administration
Siplarol side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Siplarol Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Siplarol Organisms Affected
Humans and other mammals
