Naloxone HCl
Category
Naloxone HCl Brand names, Naloxone HCl Analogs
Naloxone HCl Brand Names Mixture
Naloxone HCl Chemical_Formula
C19H21NO4
Naloxone HCl RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Naloxone HCl fda sheet
Naloxone HCl msds (material safety sheet)
Naloxone HCl Synthesis Reference
No information avaliable
Naloxone HCl Molecular Weight
327.374 g/mol
Naloxone HCl Melting Point
200 - 205 oC
Naloxone HCl H2O Solubility
Soluble
Naloxone HCl State
Solid
Naloxone HCl LogP
1.464
Naloxone HCl Dosage Forms
Liquid
Naloxone HCl Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Naloxone HCl Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Naloxone HCl Absorption
Well absorbed following intramuscular injection.
Naloxone HCl side effects and Toxicity
No information avaliable
Naloxone HCl Patient Information
No information avaliable
Naloxone HCl Organisms Affected
Humans and other mammals