Metodilazina [Inn-Spanish] en es it fr

Metodilazina [Inn-Spanish] Brand names, Metodilazina [Inn-Spanish] Analogs

Metodilazina [Inn-Spanish] Brand Names Mixture

  • No information avaliable

Metodilazina [Inn-Spanish] Chemical_Formula


Metodilazina [Inn-Spanish] RX_link

No information avaliable

Metodilazina [Inn-Spanish] fda sheet

Metodilazina [Inn-Spanish] msds (material safety sheet)

Metodilazina [Inn-Spanish] Synthesis Reference

No information avaliable

Metodilazina [Inn-Spanish] Molecular Weight

296.431 g/mol

Metodilazina [Inn-Spanish] Melting Point

87-88 oC

Metodilazina [Inn-Spanish] H2O Solubility

0.348 mg/L

Metodilazina [Inn-Spanish] State


Metodilazina [Inn-Spanish] LogP


Metodilazina [Inn-Spanish] Dosage Forms

Syrup; Tablets; Chewable tablets

Metodilazina [Inn-Spanish] Indication

Used for the symptomatic relief of hypersensitivity reactions and particularly for the control of pruritic skin disorders

Metodilazina [Inn-Spanish] Pharmacology

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Methdilazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Metodilazina [Inn-Spanish] Absorption

Well absorbed in the digestive tract.

Metodilazina [Inn-Spanish] side effects and Toxicity

Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands, and trouble in sleeping.

Metodilazina [Inn-Spanish] Patient Information

No information avaliable

Metodilazina [Inn-Spanish] Organisms Affected

Humans and other mammals