Mebendazole

Mebendazole Brand names, Mebendazole Analogs

Mebendazole Brand Names Mixture

No information avaliable

Mebendazole Chemical_Formula

C₁₆H₁₃N₃O₃

Mebendazole RX_link

http://www.rxlist.com/cgi/generic3/mebend.htm

Mebendazole fda sheet

Mebendazole msds (material safety sheet)

Mebendazole MSDS

Mebendazole Synthesis Reference

No information avaliable

Mebendazole Molecular Weight

295.293 g/mol

Mebendazole Melting Point

288.5 ^oC

Mebendazole H₂O Solubility

71.3 mg/L

Mebendazole State

Solid

Mebendazole LogP

3.291

Mebendazole Dosage Forms

Paste; Powder; 100 mg chewable tablets

Mebendazole Indication

For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.

Mebendazole Pharmacology

Mebendazole is a (synthetic) broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.

Mebendazole Absorption

Poorly absorbed (approximately 5 to 10%) from gastrointestinal tract. Fatty food increases absorption.

Mebendazole side effects and Toxicity

Acute oral toxicity (LD₅₀): 620 mg/kg [Mouse]. Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.

Mebendazole Patient Information

Mebendazole Organisms Affected

Helminthic Microorganisms