Loron en es it fr

Loron Brand names, Loron Analogs

Loron Brand Names Mixture

  • No information avaliable

Loron Chemical_Formula


Loron RX_link

No information avaliable

Loron fda sheet

Loron msds (material safety sheet)

Loron MSDS

Loron Synthesis Reference

No information avaliable

Loron Molecular Weight

244.892 g/mol

Loron Melting Point

250 oC

Loron H2O Solubility

395 mg/L

Loron State


Loron LogP


Loron Dosage Forms

Capsules; Solution

Loron Indication

For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors.

Loron Pharmacology

Clodronate is a first generation (non-nitrogenous) bisphosphonate in the same family as etidronate and tiludronate. Clodronate affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the clodronate that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Clodronate has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia.

Loron Absorption

After oral administration, absorption is estimated at 1–3% of the ingested dose because of the low uptake from the gastrointestinal tract.

Loron side effects and Toxicity

Decreases in serum calcium following substantial overdosage may be expected in some patients. Signs and symptoms of hypocalcemia also may occur in some of these patients.

Loron Patient Information

No information avaliable

Loron Organisms Affected

Humans and other mammals