Kepivance_(Amgen_Inc)
Category
Kepivance_(Amgen_Inc) Brand names, Kepivance_(Amgen_Inc) Analogs
Kepivance_(Amgen_Inc) Brand Names Mixture
No information avaliable
Kepivance_(Amgen_Inc) Chemical_Formula
C721H1142N202O204S9
Kepivance_(Amgen_Inc) RX_link
No information avaliable
Kepivance_(Amgen_Inc) fda sheet
Kepivance_(Amgen_Inc) msds (material safety sheet)
Kepivance_(Amgen_Inc) Synthesis Reference
No information avaliable
Kepivance_(Amgen_Inc) Molecular Weight
16192.7
Kepivance_(Amgen_Inc) Melting Point
No information avaliable
Kepivance_(Amgen_Inc) H2O Solubility
No information avaliable
Kepivance_(Amgen_Inc) State
Liquid
Kepivance_(Amgen_Inc) LogP
-0.650
Kepivance_(Amgen_Inc) Dosage Forms
Solution (IV Injection)
Kepivance_(Amgen_Inc) Indication
For treatment of mucositis (mouth sores)
Kepivance_(Amgen_Inc) Pharmacology
Used in the prevention or treatment of oral mucoscitis (mouth ulcers arising from chemotherapy), Kepivance binds to the human keratinocyte growth factor (KGF) receptor on buccal cell surfaces. Kepivance acts as both a cell growth and survival factor by stimulating epithelial cell proliferation, differentiation, and migration around the tongue and mouth. The KGF receptor is found on many tissues particularly around the tongue, esophagus, salivary gland and other gastro-intestinal tract organs.
Kepivance_(Amgen_Inc) Absorption
No information avaliable
Kepivance_(Amgen_Inc) Toxicity
No information avaliable
Kepivance_(Amgen_Inc) Patient Information
No information avaliable
Kepivance_(Amgen_Inc) Organisms Affected
Humans and other mammals