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Impramine Brand names, Impramine Analogs

Impramine Brand Names Mixture

  • No information avaliable

Impramine Chemical_Formula

C19H24N2

Impramine RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Impramine fda sheet

Impramine FDA

Impramine msds (material safety sheet)

Impramine Synthesis Reference

No information avaliable

Impramine Molecular Weight

280.407 g/mol

Impramine Melting Point

174.5 oC

Impramine H2O Solubility

18.2 mg/L

Impramine State

Solid

Impramine LogP

4.184

Impramine Dosage Forms

Tablet

Impramine Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Impramine Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Impramine Absorption

Rapidly and well absorbed after oral administration

Impramine side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Impramine Patient Information

Impramine Organisms Affected

Humans and other mammals