Fluoxetine
Fluoxetine Brand names, Fluoxetine Analogs
Fluoxetine Brand Names Mixture
- No information avaliable
Fluoxetine Chemical_Formula
C17H18F3NO
Fluoxetine RX_link
http://www.rxlist.com/cgi/generic/fluoxetine.htm
Fluoxetine fda sheet
Fluoxetine msds (material safety sheet)
Fluoxetine Synthesis Reference
B. B. Mally; K. K. Schmiegel; U.S. Pat. 4,314,081 (1982)
Fluoxetine Molecular Weight
309.326 g/mol
Fluoxetine Melting Point
179-182oC
Fluoxetine H2O Solubility
50 mg/mL at 25°C
Fluoxetine State
Solid
Fluoxetine LogP
5.37
Fluoxetine Dosage Forms
Capsule; Liquid; Solution
Fluoxetine Indication
For the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Fluoxetine Pharmacology
Fluoxetine, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Fluoxetine's effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level.
Fluoxetine Absorption
72%
Fluoxetine side effects and Toxicity
Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice).
Fluoxetine Patient Information
Fluoxetine Organisms Affected
Humans and other mammals
