Diketopiperazine
Category
Diketopiperazine Brand names, Diketopiperazine Analogs
Diketopiperazine Brand Names Mixture
- Canoids Cap (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Dyrex T F (Phenothiazine + Piperazine + Trichlorfon)
- Feloids Tab (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Multi Wormer for Cats (Dichlorophene + Piperazine (Piperazine Citrate))
- Multi Wormer for Dogs (Dichlorophene + Piperazine (Piperazine Citrate))
- Ripercol Horse Wormer (Piperazine (Piperazine Hydrochloride) + Tetramisole HCl)
Diketopiperazine Chemical_Formula
C4H10N2
Diketopiperazine RX_link
No information avaliable
Diketopiperazine fda sheet
Diketopiperazine msds (material safety sheet)
Diketopiperazine Synthesis Reference
No information avaliable
Diketopiperazine Molecular Weight
86.1357 g/mol
Diketopiperazine Melting Point
106 oC
Diketopiperazine H2O Solubility
150 mg/mL
Diketopiperazine State
Solid
Diketopiperazine LogP
-0.836
Diketopiperazine Dosage Forms
Capsule; Drops; Liquid; Powder; Powder for solution; Solution; Suspension; Syrup; Tablet
Diketopiperazine Indication
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
Diketopiperazine Pharmacology
Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.
Diketopiperazine Absorption
Rapidly absorbed from the gastrointestinal tract
Diketopiperazine side effects and Toxicity
LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.
Diketopiperazine Patient Information
No information avaliable
Diketopiperazine Organisms Affected
Parasitic nematodes and other roundworms