Dermatop
Dermatop Brand names, Dermatop Analogs
Dermatop Brand Names Mixture
- No information avaliable
Dermatop Chemical_Formula
C16H21NO2
Dermatop RX_link
http://www.rxlist.com/cgi/generic4/rozerem.htm
Dermatop fda sheet
Dermatop msds (material safety sheet)
Dermatop Synthesis Reference
No information avaliable
Dermatop Molecular Weight
259.343 g/mol
Dermatop Melting Point
No information avaliable
Dermatop H2O Solubility
No information avaliable
Dermatop State
No information avaliable
Dermatop LogP
2.536
Dermatop Dosage Forms
No information avaliable
Dermatop Indication
For the treatment of insomnia characterized by difficulty with sleep onset.
Dermatop Pharmacology
Ramelton is the first selective melatonin agonist. It works by mimicing melatonin (MT), a naturally occuring hormone that is produced during the sleep period. It has a high affinity for the MT1 and MT2 receptor. The MT1 and MT2 receptors are located in the brain's suprachiasmatic nuclei (SCN). The SCN is known as the body's "master clock" because it regulates the 24-hour sleep-wake cycle. Ramelton has an active metabolite that is less potent but circulates in higher concentrations than the parent compound. The metabolite also has weak affinity for the 5HT2b receptor.
Dermatop Absorption
Rapid, total absorption is at least 84%.
Dermatop side effects and Toxicity
No information avaliable
Dermatop Patient Information
Dermatop Organisms Affected
Humans and other mammals
