Deoxyribonuclease-1 precursor
Deoxyribonuclease-1 precursor Brand names, Deoxyribonuclease-1 precursor Analogs
Deoxyribonuclease-1 precursor Brand Names Mixture
- No information avaliable
Deoxyribonuclease-1 precursor Chemical_Formula
C1321H1999N339O396S9
Deoxyribonuclease-1 precursor RX_link
http://www.rxlist.com/cgi/generic3/pulmozyme.htm
Deoxyribonuclease-1 precursor fda sheet
Deoxyribonuclease-1 precursor msds (material safety sheet)
Deoxyribonuclease-1 precursor Synthesis Reference
No information avaliable
Deoxyribonuclease-1 precursor Molecular Weight
29253.9
Deoxyribonuclease-1 precursor Melting Point
67 oC (Chan, H.K. et al., Pharm Res. 13:756-761 (1996))
Deoxyribonuclease-1 precursor H2O Solubility
No information avaliable
Deoxyribonuclease-1 precursor State
Liquid
Deoxyribonuclease-1 precursor LogP
-0.083
Deoxyribonuclease-1 precursor Dosage Forms
Solution
Deoxyribonuclease-1 precursor Indication
For treatment of cystic fibrosis
Deoxyribonuclease-1 precursor Pharmacology
Cystic fibrosis (CF) is a disease characterized by the retention of viscous purulent secretions in the airways. These thick secretions contribute both to reduced pulmonary function and to frequent pulmonary infection. Purulent pulmonary secretions contain very high concentrations of extracellular DNA released by degenerating leukocytes that accumulate in response to these infections. Pulmozyme hydrolyzes the DNA in sputum of CF patients and reduces sputum viscoelasticity.
Deoxyribonuclease-1 precursor Absorption
No information avaliable
Deoxyribonuclease-1 precursor side effects and Toxicity
No information avaliable
Deoxyribonuclease-1 precursor Patient Information
BIOD00001.html
Deoxyribonuclease-1 precursor Organisms Affected
Humans and other mammals
