Cloxacillin
Cloxacillin Brand names, Cloxacillin Analogs
Cloxacillin Brand Names Mixture
- No information avaliable
Cloxacillin Chemical_Formula
C19H18ClN3O5S
Cloxacillin RX_link
No information avaliable
Cloxacillin fda sheet
Cloxacillin msds (material safety sheet)
Cloxacillin Synthesis Reference
No information avaliable
Cloxacillin Molecular Weight
435.882 g/mol
Cloxacillin Melting Point
No information avaliable
Cloxacillin H2O Solubility
13.9 mg/L
Cloxacillin State
Solid
Cloxacillin LogP
2.274
Cloxacillin Dosage Forms
Capsules (250 mg, 500 mg); Powder (125 mg/5 mL when reconstituted)
Cloxacillin Indication
Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
Cloxacillin Pharmacology
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is for use against staphylococci that produce beta-lactamase.
Cloxacillin Absorption
Well absorbed from the gastrointestinal tract.
Cloxacillin side effects and Toxicity
Oral LD50 in rat and mouse is 5000 mg/kg. Intravenous LD50 in rat is 1660 mg/kg. Symptoms of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, and swelling of face, lips, tongue, or throat.
Cloxacillin Patient Information
Cloxacillin Organisms Affected
Enteric bacteria and other eubacteria
