Butanoic acid, 2-amino-4-(methylthio)-, (S)-
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Brand names, Butanoic acid, 2-amino-4-(methylthio)-, (S)- Analogs
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Brand Names Mixture
- No information avaliable
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Chemical_Formula
C5H11N1O2S1
Butanoic acid, 2-amino-4-(methylthio)-, (S)- RX_link
No information avaliable
Butanoic acid, 2-amino-4-(methylthio)-, (S)- fda sheet
Butanoic acid, 2-amino-4-(methylthio)-, (S)- msds (material safety sheet)
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Synthesis Reference
No information avaliable
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Molecular Weight
149.207 g/mol
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Melting Point
276-279 oC
Butanoic acid, 2-amino-4-(methylthio)-, (S)- H2O Solubility
No information avaliable
Butanoic acid, 2-amino-4-(methylthio)-, (S)- State
Solid
Butanoic acid, 2-amino-4-(methylthio)-, (S)- LogP
-2.308
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Dosage Forms
Capsules, powder and tablets
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Indication
Used for protein synthesis including the formation of SAMe, L-homocysteine, L-cysteine, taurine, and sulfate.
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Pharmacology
Is a principle supplier of sulfur which prevents disorders of the hair, skin and nails; helps lower cholesterol levels by increasing the liver's production of lecithin; reduces liver fat and protects the kidneys; a natural chelating agent for heavy metals; regulates the formation of ammonia and creates ammonia-free urine which reduces bladder irritation; influences hair follicles and promotes hair growth. L-methionine may protect against the toxic effects of hepatotoxins, such as acetaminophen. Methionine may have antioxidant activity.
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Absorption
Absorbed from the lumen of the small intestine into the enterocytes by an active transport process.
Butanoic acid, 2-amino-4-(methylthio)-, (S)- side effects and Toxicity
Doses of L-methionine of up to 250 mg daily are generally well tolerated. Higher doses may cause nausea, vomiting and headache. Healthy adults taking 8 grams of L-methionine daily for four days were found to have reduced serum folate levels and leucocytosis. Healthy adults taking 13.9 grams of L-methionine daily for five days were found to have changes in serum pH and potassium and increased urinary calcium excretion. Schizophrenic patients given 10 to 20 grams of L-methionine daily for two weeks developed functional psychoses. Single doses of 8 grams precipitated encephalopathy in patients with cirrhosis.
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Patient Information
There are no indications for the use of supplemental methionine unless specifically recommended by a physician. It is effective as an antidote in some cases of acetaminophen poisoning. But, because some research suggests that it may promote some cancers, its use as a supplement is inadvisable.
Butanoic acid, 2-amino-4-(methylthio)-, (S)- Organisms Affected
Humans and other mammals
