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Aplexal Brand names, Aplexal Analogs

Aplexal Brand Names Mixture

  • No information avaliable

Aplexal Chemical_Formula

C26H28N2

Aplexal RX_link

No information avaliable

Aplexal fda sheet

Aplexal msds (material safety sheet)

Aplexal Synthesis Reference

No information avaliable

Aplexal Molecular Weight

368.514 g/mol

Aplexal Melting Point

No information avaliable

Aplexal H2O Solubility

750 mg/L

Aplexal State

Solid

Aplexal LogP

5.63

Aplexal Dosage Forms

No information avaliable

Aplexal Indication

For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.

Aplexal Pharmacology

Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.

Aplexal Absorption

No information avaliable

Aplexal side effects and Toxicity

No information avaliable

Aplexal Patient Information

No information avaliable

Aplexal Organisms Affected

Humans and other mammals