Antibiotic 2233wp en es it fr

Antibiotic 2233wp Brand names, Antibiotic 2233wp Analogs

Antibiotic 2233wp Brand Names Mixture

  • No information avaliable

Antibiotic 2233wp Chemical_Formula


Antibiotic 2233wp RX_link

Antibiotic 2233wp fda sheet

Antibiotic_2233wp FDA

Antibiotic 2233wp msds (material safety sheet)

Antibiotic_2233wp MSDS

Antibiotic 2233wp Synthesis Reference

No information avaliable

Antibiotic 2233wp Molecular Weight

351.463 g/mol

Antibiotic 2233wp Melting Point

No information avaliable

Antibiotic 2233wp H2O Solubility


Antibiotic 2233wp State


Antibiotic 2233wp LogP


Antibiotic 2233wp Dosage Forms

Cream or gel (0.05% or 0.1%)

Antibiotic 2233wp Indication

Used to treat psoriasis, acne and sun damaged skin (photodamage).

Antibiotic 2233wp Pharmacology

Tazarotene is a prodrug and a member of the acetylenic class of retinoids. Following topical application, tazarotene undergoes esterase hydrolysis to form its active metabolite, tazarotenic acid. When treating acne tazarotene may be taken in conjunction with an oral antibiotic. Tazarotene has been shown in peer-reviewed double blinded studies to reduce: mottling and hyperpigmentation, sallowness, fine wrinkling and coarse wrinkling in sun damaged skin. Histological studies have shown that long term (greater than 1 year) use of Tazarotene is associated with a significant reduction in atypical melanocytes and keratocytes - cells considered to be precursors of skin cancer. Some studies have shown long term use of Tazarotene to be associated with increased collagen production and better organization of skin collagen bundles.

Antibiotic 2233wp Absorption

Minimal systemic absorption of tazarotene occurs due to its rapid metabolism in the skin to the active metabolite, tazarotenic acid, which can be systemically absorbed and further metabolized. Gender had no influence on the systemic bioavailability of tazarotenic acid.

Antibiotic 2233wp side effects and Toxicity

Excessive topical use may lead to marked redness, peeling, or discomfort. Oral ingestion of the drug may affect liver function causing hypertriglyceridemia. Other symptoms may include conjunctival irritation, hair loss, headache, edema, fatigue, dermatitis, nausea, and visual disturbances. Oral administration of this material to rats and rabbits at doses of 0.20 mg/kg/day (rabbits) and 0.25 mg/kg/day (rats) resulted in developmental toxicity. A no effect level of 0.05 mg/kg/day was established. Similar teratogenic effects have been reported for other retinoid compounds.

Antibiotic 2233wp Patient Information

Antibiotic 2233wp Organisms Affected

Humans and other mammals