Antalgin
Category
Antalgin Brand names, Antalgin Analogs
Antalgin Brand Names Mixture
Antalgin Chemical_Formula
C17H23NO
Antalgin RX_link
http://www.rxlist.com/cgi/generic2/levorphanol.htm
Antalgin fda sheet
Antalgin msds (material safety sheet)
Antalgin Synthesis Reference
Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.
Antalgin Molecular Weight
257.371 g/mol
Antalgin Melting Point
198-199 oC
Antalgin H2O Solubility
1840 mg/L
Antalgin State
Solid
Antalgin LogP
3.986
Antalgin Dosage Forms
Tablet
Antalgin Indication
For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate
Antalgin Pharmacology
Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.
Antalgin Absorption
Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.
Antalgin side effects and Toxicity
LD50=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.
Antalgin Patient Information
No information avaliable
Antalgin Organisms Affected
Humans and other mammals
