5,6,7,8 Tetrahydrobiopterin

5,6,7,8 Tetrahydrobiopterin Brand names, 5,6,7,8 Tetrahydrobiopterin Analogs

5,6,7,8 Tetrahydrobiopterin Brand Names Mixture

No information avaliable

5,6,7,8 Tetrahydrobiopterin Chemical_Formula

C₂₂H₂₂FN₃O₂

5,6,7,8 Tetrahydrobiopterin RX_link

http://www.rxlist.com/cgi/generic3/droperidol.htm

5,6,7,8 Tetrahydrobiopterin fda sheet

5,6,7,8 Tetrahydrobiopterin msds (material safety sheet)

5,6,7,8_Tetrahydrobiopterin MSDS

5,6,7,8 Tetrahydrobiopterin Synthesis Reference

No information avaliable

5,6,7,8 Tetrahydrobiopterin Molecular Weight

379.428 g/mol

5,6,7,8 Tetrahydrobiopterin Melting Point

145.75 ^oC

5,6,7,8 Tetrahydrobiopterin H₂O Solubility

4.21 mg/L

5,6,7,8 Tetrahydrobiopterin State

Solid

5,6,7,8 Tetrahydrobiopterin LogP

2.791

5,6,7,8 Tetrahydrobiopterin Dosage Forms

Liquid; Solution

5,6,7,8 Tetrahydrobiopterin Indication

Used to produce tranquilization and to reduce the incidence of nausea and vomiting in surgical and diagnostic procedures.

5,6,7,8 Tetrahydrobiopterin Pharmacology

Droperidol produces marked tranquilization and sedation. It allays apprehension and provides a state of mental detachment and indifference while maintaining a state of reflex alertness. Droperidol produces an antiemetic effect as evidenced by the antagonism of apomorphine in dogs. It lowers the incidence of nausea and vomiting during surgical procedures and provides antiemetic protection in the postoperative period. Droperidol potentiates other CNS depressants. It produces mild alpha-adrenergic blockade, peripheral vascular dilatation and reduction of the pressor effect of epinephrine. It can produce hypotension and decreased peripheral vascular resistance and may decrease pulmonary arterial pressure (particularly if it is abnormally high). It may reduce the incidence of epinephrine-induced arrhythmias, but it does not prevent other cardiac arrhythmias.

5,6,7,8 Tetrahydrobiopterin Absorption

Completely absorbed following intramuscular administration.

5,6,7,8 Tetrahydrobiopterin side effects and Toxicity

The intravenous LD₅₀ of droperidol is 20-43 mg/kg in mice; 30 mg/kg in rats; 25 mg/kg in dogs and 11-13 mg/kg in rabbits. The intramuscular LD₅₀ of droperidol is 195 mg/kg in mice, 104-110 mg/kg in rats; 97 mg/kg in rabbits and 200 mg/kg in guinea pigs. The manifestations of droperidol overdosage are an extension of its pharmacologic actions.

5,6,7,8 Tetrahydrobiopterin Patient Information

5,6,7,8 Tetrahydrobiopterin Organisms Affected

Humans and other mammals