tPA en es it fr

tPA Brand names, tPA Analogs

tPA Brand Names Mixture

  • No information avaliable

tPA Chemical_Formula

C1736H2671N499O522S22

tPA RX_link

http://www.rxlist.com/cgi/generic2/reteplase.htm

tPA fda sheet

tPA msds (material safety sheet)

tPA Synthesis Reference

No information avaliable

tPA Molecular Weight

39589.6

tPA Melting Point

60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))

tPA H2O Solubility

No information avaliable

tPA State

Liquid

tPA LogP

-0.435

tPA Dosage Forms

Solution (IV injection); Powder for solution

tPA Indication

For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction

tPA Pharmacology

Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.

tPA Absorption

No information avaliable

tPA side effects and Toxicity

No information avaliable

tPA Patient Information

No information avaliable

tPA Organisms Affected

Humans and other mammals