Polymixin B sulfate

MSDS Language: EN
Country:
                      **** MATERIAL SAFETY DATA SHEET ****

  2,6-Diisopropylphenol, 99%

        **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: 2,6-Diisopropylphenol, 99%
Catalog Numbers:
     33482-0000, 33482-0050, 33482-0250
Synonyms:
Company Identification (Europe):  Acros Organics BVBA
                                  Janssen Pharmaceuticalaan 3a
                                  2440 Geel, Belgium
Company Identification (USA):     Acros Organics
                                  One Reagent Lane
                                  Fairlawn, NJ  07410
For information in North America, call:   800-ACROS-01
For information in Europe, call:          0032(0) 14575211
For emergencies in the US, call CHEMTREC: 800-424-9300
For emergencies in Europe, call:     0032(0) 14575299

          **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+-----------+---------------+
|      CAS#      |              Chemical Name           |    %     |  EINECS#  |Haz Symbols| Risk Phrases  |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
|     2078-54-8  |2,6-Diisopropylphenol                 |   99%    | 218-206-6 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
          Hazard Symbols: XN
          Risk Phrases: 22 36/37/38

                  **** SECTION 3 - HAZARDS IDENTIFICATION ****

                               EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to eyes, respiratory system and
skin.Air sensitive.

Potential Health Effects
     Eye:
          Causes eye irritation.
     Skin:
          Causes skin irritation.
     Ingestion:
          Harmful if swallowed. May cause irritation of the digestive tract.
     Inhalation:
          Dust is irritating to the respiratory tract. The toxicological
          properties of this substance have not been fully investigated.
     Chronic:
          Not available.

                    **** SECTION 4 - FIRST AID MEASURES ****

     Eyes:
          Flush eyes with plenty of water for at least 15 minutes,
          occasionally lifting the upper and lower eyelids. Get medical aid.
     Skin:
          Get medical aid. Flush skin with plenty of water for at least 15
          minutes while removing contaminated clothing and shoes.
     Ingestion:
          Get medical aid. Wash mouth out with water.
     Inhalation:
          Remove from exposure and move to fresh air immediately. If not
          breathing, give artificial respiration. If breathing is difficult,
          give oxygen. Get medical aid.
     Notes to Physician:

                  **** SECTION 5 - FIRE FIGHTING MEASURES ****

     General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear.
     Extinguishing Media:
          In case of fire, use water, dry chemical, chemical foam, or
          alcohol-resistant foam.

                **** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

     General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     Spills/Leaks:
          Absorb spill with inert material (e.g. vermiculite, sand or earth),
          then place in suitable container.

                   **** SECTION 7 - HANDLING and STORAGE ****

     Handling:
          Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes,
          skin, and clothing. Use only in a chemical fume hood.
     Storage:
          Store in a cool, dry place. Store in a tightly closed container.
          Keep under an argon blanket. Keep refrigerated. (Store below
          4�C/39�F.)

          **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

     Engineering Controls:
          Use adequate general or local exhaust ventilation to keep airborne
          concentrations below the permissible exposure limits.
     Personal Protective Equipment

                 Eyes:
                       Wear appropriate protective eyeglasses or chemical
                       safety goggles as described by OSHA's eye and face
                       protection regulations in 29 CFR 1910.133 or European
                       Standard EN166.
                 Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          Respirators:
                       Follow the OSHA respirator regulations found in 29
                       CFR 1910.134 or European Standard EN 149. Always use
                       a NIOSH or European Standard EN 149 approved
                       respirator when necessary.

             **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State:             Clear liquid
Color:                      colorless to yellow
Odor:                       Not available.
pH:                         Not available.
Vapor Pressure:             Not available.
Viscosity:                  Not available.
Boiling Point:              256 deg C @ 764.00mm Hg
Freezing/Melting Point:     18 deg C
Autoignition Temperature:   Not available.
Flash Point:                > 112 deg C (> 233.60 deg F)
Explosion Limits, lower:    Not available.
Explosion Limits, upper:    Not available.
Decomposition Temperature:
Solubility in water:        soluble in toluene and alcohol
Specific Gravity/Density:   .9620g/cm3
Molecular Formula:
Molecular Weight:           178.27

                 **** SECTION 10 - STABILITY AND REACTIVITY ****

     Chemical Stability:
          Stable under normal temperatures and pressures.
     Conditions to Avoid:
          Incompatible materials.
     Incompatibilities with Other Materials:
          Oxidizing agents, bases, acid chlorides, acid anhydrides.
     Hazardous Decomposition Products:
          Carbon monoxide, carbon dioxide.
     Hazardous Polymerization: Has not been reported.

                **** SECTION 11 - TOXICOLOGICAL INFORMATION ****

     RTECS#:
          CAS# 2078-54-8: SL0810000
     LD50/LC50:
          CAS# 2078-54-8: Oral, mouse: LD50 = 1100 mg/kg; Oral, rat: LD50 =
          500 mg/kg.
     Carcinogenicity:
       2,6-Diisopropylphenol -
          Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
          See actual entry in RTECS for complete information.

                  **** SECTION 12 - ECOLOGICAL INFORMATION ****



                 **** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

                  **** SECTION 14 - TRANSPORT INFORMATION ****

     IATA
          Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S.*
           Hazard Class: 8
              UN Number: 2922
          Packing Group: III
     IMO
          Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S.
           Hazard Class: 8
              UN Number: 2922
          Packing Group: III
     RID/ADR
          Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S.
           Hazard Class: 8
              UN Number: 2922
          Packing group: III

                  **** SECTION 15 - REGULATORY INFORMATION ****

 European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols: XN
          Risk Phrases:
                       R 22  Harmful if swallowed.
                       R 36/37/38  Irritating to eyes, respiratory system
                       and skin.
          Safety Phrases:
                       S 26  In case of contact with eyes, rinse immediately
                       with plenty of water and seek medical advice.
                       S 37/39  Wear suitable gloves and eye/face
                       protection.
   WGK (Water Danger/Protection)
          CAS# 2078-54-8: No information available.
   United Kingdom Occupational Exposure Limits

   United Kingdom Maximum Exposure Limits

   Canada
          CAS# 2078-54-8 is listed on Canada's DSL List.
          CAS# 2078-54-8 is not listed on Canada's Ingredient Disclosure List.
   Exposure Limits
 US FEDERAL
     TSCA
          CAS# 2078-54-8 is listed on the TSCA inventory.

                  **** SECTION 16 - ADDITIONAL INFORMATION ****

     MSDS Creation Date: 11/16/1998  Revision #0 Date: Original.

     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no way shall the company be
     liable for any claims, losses, or damages of any third party or for lost
     profits or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if the company has been advised of
     the possibility of such damages.
--------------------------------------------------------------------------------