P. V. Carbachol

MSDS Language: EN
Country:
                      **** MATERIAL SAFETY DATA SHEET ****

  Carbamylcholine chloride, 99%

        **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: Carbamylcholine chloride, 99%
Catalog Numbers:
     10824-0000, 10824-0100, 10824-0250, 10824-1000
Synonyms:
     Carbachol; (2-Hydroxyethyl)trimethylammonium chloride carbamate
Company Identification (Europe):  Acros Organics BVBA
                                  Janssen Pharmaceuticalaan 3a
                                  2440 Geel, Belgium
Company Identification (USA):     Acros Organics
                                  One Reagent Lane
                                  Fairlawn, NJ  07410
For information in North America, call:   800-ACROS-01
For information in Europe, call:          0032(0) 14575211
For emergencies in the US, call CHEMTREC: 800-424-9300
For emergencies in Europe, call:     0032(0) 14575299

          **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+-----------+---------------+
|      CAS#      |              Chemical Name           |    %     |  EINECS#  |Haz Symbols| Risk Phrases  |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
|       51-83-2  |Carbamylcholine chloride              |   99%    | 200-127-3 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
          Hazard Symbols: T
          Risk Phrases: 25

                  **** SECTION 3 - HAZARDS IDENTIFICATION ****

                               EMERGENCY OVERVIEW
Toxic if swallowed.Hygroscopic (absorbs moisture from the air).

Potential Health Effects
     Eye:
          May cause eye irritation.
     Skin:
          May cause skin irritation.
     Ingestion:
          Poison by ingestion.
     Inhalation:
          May cause respiratory tract irritation. The toxicological properties
          of this substance have not been fully investigated.
     Chronic:
          Not available.

                    **** SECTION 4 - FIRST AID MEASURES ****

     Eyes:
          Immediately flush eyes with plenty of water for at least 15 minutes,
          occasionally lifting the upper and lower eyelids. Get medical aid
          immediately.
     Skin:
          Get medical aid immediately. Immediately flush skin with plenty of
          water for at least 15 minutes while removing contaminated clothing
          and shoes.
     Ingestion:
          Get medical aid immediately. Wash mouth out with water.
     Inhalation:
          Get medical aid immediately. Remove from exposure and move to fresh
          air immediately. If not breathing, give artificial respiration. If
          breathing is difficult, give oxygen.
     Notes to Physician:

                  **** SECTION 5 - FIRE FIGHTING MEASURES ****

     General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear.
     Extinguishing Media:
          Use water spray, dry chemical, carbon dioxide, or chemical foam.

                **** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

     General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     Spills/Leaks:
          Vacuum or sweep up material and place into a suitable disposal
          container.

                   **** SECTION 7 - HANDLING and STORAGE ****

     Handling:
          Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on
          skin, or on clothing. Use only in a chemical fume hood.
     Storage:
          Store in a cool, dry place. Store in a tightly closed container.

          **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

     Engineering Controls:
          Use adequate ventilation to keep airborne concentrations low.
     Personal Protective Equipment

                 Eyes:
                       Wear appropriate protective eyeglasses or chemical
                       safety goggles as described by OSHA's eye and face
                       protection regulations in 29 CFR 1910.133 or European
                       Standard EN166.
                 Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          Respirators:
                       Follow the OSHA respirator regulations found in 29
                       CFR 1910.134 or European Standard EN 149. Always use
                       a NIOSH or European Standard EN 149 approved
                       respirator when necessary.

             **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State:             Crystalline powder
Color:                      white
Odor:                       odorless
pH:                         Not available.
Vapor Pressure:             Not available.
Viscosity:                  Not available.
Boiling Point:              Not available.
Freezing/Melting Point:     200 - 204 deg C
Autoignition Temperature:   Not available.
Flash Point:                Not available.
Explosion Limits, lower:    Not available.
Explosion Limits, upper:    Not available.
Decomposition Temperature:  >210 deg C
Solubility in water:        1 g/ml water
Specific Gravity/Density:
Molecular Formula:          H2NCO2CH2CH2N(CH3)3Cl
Molecular Weight:           182.65

                 **** SECTION 10 - STABILITY AND REACTIVITY ****

     Chemical Stability:
          Not available.
     Conditions to Avoid:
          Incompatible materials.
     Incompatibilities with Other Materials:
          Strong oxidizing agents.
     Hazardous Decomposition Products:
          Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
     Hazardous Polymerization: Has not been reported.

                **** SECTION 11 - TOXICOLOGICAL INFORMATION ****

     RTECS#:
          CAS# 51-83-2: GA0875000
     LD50/LC50:
          CAS# 51-83-2: Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40
          mg/kg.
     Carcinogenicity:
       Carbamylcholine chloride -
          Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
          See actual entry in RTECS for complete information.

                  **** SECTION 12 - ECOLOGICAL INFORMATION ****



                 **** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

                  **** SECTION 14 - TRANSPORT INFORMATION ****

     IATA
          Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
           Hazard Class: 6.1
              UN Number: 2811
          Packing Group: II
     IMO
          Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
           Hazard Class: 6.1
              UN Number: 2811
          Packing Group: II
     RID/ADR
          Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
           Hazard Class: 6.1
              UN Number: 2811
          Packing group: II

                  **** SECTION 15 - REGULATORY INFORMATION ****

 European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols: T
          Risk Phrases:
                       R 25  Toxic if swallowed.
          Safety Phrases:
                       S 28A  After contact with skin, wash immediately with
                       plenty of water.
                       S 45  In case of accident or if you feel unwell, seek
                       medical advice immediately (show the label where
                       possible).
   WGK (Water Danger/Protection)
          CAS# 51-83-2: No information available.
   United Kingdom Occupational Exposure Limits

   United Kingdom Maximum Exposure Limits

   Canada
          CAS# 51-83-2 is listed on Canada's NDSL List.
          CAS# 51-83-2 is not listed on Canada's Ingredient Disclosure List.
   Exposure Limits
 US FEDERAL
     TSCA
          CAS# 51-83-2 is listed on the TSCA inventory.

                  **** SECTION 16 - ADDITIONAL INFORMATION ****

     MSDS Creation Date: 10/25/1996  Revision #0 Date: Original.

     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no way shall the company be
     liable for any claims, losses, or damages of any third party or for lost
     profits or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if the company has been advised of
     the possibility of such damages.
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