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                      **** MATERIAL SAFETY DATA SHEET ****

  Mannitol
88721

        **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: Mannitol
Catalog Numbers:
     BP/M220, M/2400, M/2405
Synonyms:
     D-Manninol, Isotol
Company Identification:  Fisher Scientific UK
                         Bishop Meadow Road
                         Loughborough, Leicestershire
                         LE11 5RG, UK
For information, call:   01509 231166
For emergencies, call:   01509 231166

          **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+-----------+---------------+
|      CAS#      |              Chemical Name           |    %     |  EINECS#  |Haz Symbols| Risk Phrases  |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
|       69-65-8  |D-mannitol                            |   100%   | 200-711-8 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
          Hazard Symbols: None Listed.
          Risk Phrases: None Listed.

                  **** SECTION 3 - HAZARDS IDENTIFICATION ****

                               EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully
investigated.

Potential Health Effects
     Eye:
          May cause eye irritation.
     Skin:
          May cause skin irritation. Low hazard for usual industrial handling.
     Ingestion:
          Ingestion of large amounts may cause gastrointestinal irritation.
          Expected to be a low ingestion hazard.
     Inhalation:
          May cause respiratory tract irritation. Low hazard for usual
          industrial handling.
     Chronic:
          No information found.

                    **** SECTION 4 - FIRST AID MEASURES ****

     Eyes:
          Immediately flush eyes with plenty of water for at least 15 minutes,
          occasionally lifting the upper and lower eyelids. Get medical aid
          immediately.
     Skin:
          Immediately flush skin with plenty of water for at least 15 minutes
          while removing contaminated clothing and shoes. Get medical aid if
          irritation develops or persists.
     Ingestion:
          If victim is conscious and alert, give 2-4 cupfuls of milk or water.
          Get medical aid immediately.
     Inhalation:
          Remove from exposure and move to fresh air immediately. If not
          breathing, give artificial respiration. If breathing is difficult,
          give oxygen. Get medical aid.
     Notes to Physician:

                  **** SECTION 5 - FIRE FIGHTING MEASURES ****

     General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear. Dusts at sufficient concentrations can form
          explosive mixtures with air.
     Extinguishing Media:
          For small fires, use water spray, dry chemical, carbon dioxide or
          chemical foam.

                **** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

     General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     Spills/Leaks:
          Wash area with soap and water. Clean up spills immediately,
          observing precautions in the Protective Equipment section. Sweep up,
          then place into a suitable container for disposal. Avoid generating
          dusty conditions. Provide ventilation.

                   **** SECTION 7 - HANDLING and STORAGE ****

     Handling:
          Wash thoroughly after handling. Use with adequate ventilation. Avoid
          contact with skin and eyes. Avoid ingestion and inhalation.
     Storage:
          Store in a cool, dry place. Keep from contact with oxidizing
          materials.

          **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

     Engineering Controls:
          Use adequate general or local exhaust ventilation to keep airborne
          concentrations below the permissible exposure limits.
     Personal Protective Equipment

                 Eyes:
                       Not available.
                 Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          Respirators:
                       Follow the OSHA respirator regulations found in 29
                       CFR 1910.134 or European Standard EN 149. Always use
                       a NIOSH or European Standard EN 149 approved
                       respirator when necessary.

             **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State:             Solid
Color:                      white
Odor:                       Odorless.
pH:                         Not available.
Vapor Pressure:             Negligible.
Viscosity:                  Not available.
Boiling Point:              Not available.
Freezing/Melting Point:     167 deg C
Autoignition Temperature:   Not available.
Flash Point:                Not available.
Explosion Limits, lower:    Not available.
Explosion Limits, upper:    Not available.
Decomposition Temperature:  Not available.
Solubility in water:        Soluble in water.
Specific Gravity/Density:   Not available.
Molecular Formula:          C6H14O6
Molecular Weight:           182.0944

                 **** SECTION 10 - STABILITY AND REACTIVITY ****

     Chemical Stability:
          Stable under normal temperatures and pressures.
     Conditions to Avoid:
          Incompatible materials.
     Incompatibilities with Other Materials:
          Oxidizing agents.
     Hazardous Decomposition Products:
          Carbon monoxide, carbon dioxide.
     Hazardous Polymerization: Has not been reported.

                **** SECTION 11 - TOXICOLOGICAL INFORMATION ****

     RTECS#:
          CAS# 69-65-8: OP2060000
     LD50/LC50:
          CAS# 69-65-8: Oral, mouse: LD50 = 22 gm/kg; Oral, rat: LD50 = 13500
          mg/kg.
     Carcinogenicity:
       D-mannitol -
          Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
          See actual entry in RTECS for complete information.

                  **** SECTION 12 - ECOLOGICAL INFORMATION ****



                 **** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location.  Contact a specialist disposal company or the local
waste regulator for advice.  Empty containers must be decontaminated before
returning for recycling.

                  **** SECTION 14 - TRANSPORT INFORMATION ****

     IATA
          Not regulated as a hazardous material.
     IMO
          Not regulated as a hazardous material.
     RID/ADR
          Not regulated as a hazardous material.

                  **** SECTION 15 - REGULATORY INFORMATION ****

 European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols: Not available.
          Risk Phrases:
          Safety Phrases:
   WGK (Water Danger/Protection)
          CAS# 69-65-8: 0
   United Kingdom Occupational Exposure Limits

   United Kingdom Maximum Exposure Limits

   Canada
          CAS# 69-65-8 is listed on Canada's DSL List.
          CAS# 69-65-8 is not listed on Canada's Ingredient Disclosure List.
   Exposure Limits
 US FEDERAL
     TSCA
          CAS# 69-65-8 is listed on the TSCA inventory.

                  **** SECTION 16 - ADDITIONAL INFORMATION ****

     MSDS Creation Date:  6/23/2004  Revision #0 Date: Original.

     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no way shall the company be
     liable for any claims, losses, or damages of any third party or for lost
     profits or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if the company has been advised of
     the possibility of such damages.
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