Isoniazid

Safety (MSDS) data for isoniazid  

Safety (MSDS) data for isoniazid

Hazard: toxic


General

    Synonyms: isonicotinic acid hydrazide, anidon, 4-pyridinecarboxylic acid hydrazide, bacillen, cedin, cemidon, dibutin, gink, HIA, hidranizil, iscotin, isolyn, very large number of other trade names.
    Use: antibacterial and anti-tubercular agent
    Molecular formula: C6H7N3O
    CAS No: 54-85-3
    EC No:

Physical data

    Appearance: white crystalline powder
    Melting point: 171 C
    Boiling point:
    Vapour density:
    Vapour pressure:
    Density (g cm-3):
    Flash point: 190 C
    Explosion limits:
    Autoignition temperature:
    Water solubility: substantial
     

Stability

    Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites.

Toxicology

    Poison. Experimental carcinogen, neoplastigen, tumorigen. Human mutagenic data. Experimental teratogen. May cause reproductive defects.

    Toxicity data
    (The meaning of any abbreviations which appear in this section is given here.)
    ORL-HMN LDLO 100 mg kg-1
    ORL-MAN TDLO 430 mg kg-1
    ORL-DOG LD50 50 mg kg-1
    IVN-MUS LD50 149 mg kg-1
    SCU-RAT LD50 329 mg kg-1
    ORL-GPG LD50 255 mg kg-1

    Risk phrases
    (The meaning of any risk phrases which appear in this section is given here.)
    R23 R24 R25 R47.

Transport information

Personal protection

    Treat as potentially hazardous. Safety glasses, gloves, good ventilation.

    Safety phrases
    (The meaning of any safety phrases which appear in this section is given here.)

[Return to Physical & Theoretical Chemistry Lab. Safety home page.]


This information was last updated on May 13, 2005. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.