Halothane

Safety (MSDS) data for 2-bromo-2-chloro-1,1,1-trifluoroethane

Safety (MSDS) data for 2-bromo-2-chloro-1,1,1-trifluoroethane

Hazard: harmful


General

    Synonyms: bromochlorotrifluoroethane, 1-bromo-1-chloro-2,2,2-trifluoroethane, chalothane, fluorotane, fluothane, anestan, halotan, halothane, halsan, halotane, narcotan, halan, rhodialothan, Freon 123b1, narcotane, various further names
    Use: inhalation anaesthetic
    Molecular formula: C2HBrClF3
    CAS No: 151-67-7
    EINECS No: 205-796-5

Physical data

    Appearance: colourless liquid
    Melting point:
    Boiling point: 50 C
    Vapour density: 6.8 (calculated, air=1)
    Vapour pressure: 232 mm Hg at 20C
    Density (g cm-3): 1.872
    Flash point:
    Explosion limits:
    Autoignition temperature:
    Water solubility: slight

Stability

    Stable, but may be light sensitive. Incompatible with rubber, plastics, strong oxidizing agents. Tarnishes most metals. Non-combustible. May be stabilized with 0.01% thymol.

Toxicology

    Severe eye irritant. May act as a carcinogen or mutagen. May cause reproductive damage. Experimental teratogen. Harmful if inhaled. May be harmful in contact with the skin or if swallowed. Narcotic. Ceiling limit 2 ppm.

    Toxicity data
    (The meaning of any toxicological abbreviations which appear in this section is given here.)
    ORL-HMN LDLO 140 mg kg-1
    IHL-HMN LCLO 7000 ppm/3h
    IVN-MAN LDLO 129 mg kg-1
    ORL-RAT LD50 5680 mg kg-1
    IHL-RAT LC50 29000 ppm
    IHL-MUS LC50 98 g/m3/2h
    ORL-GPG LD50 6000 mg kg-1

    Risk phrases
    (The meaning of any risk phrases which appear in this section is given here.)
    R20 R36 R40 R61.

Transport information

    (The meaning of any UN hazard codes which appear in this section is given here.)
    Aviation regulated liquid. UN No 3334. Major hazard class 9.0.

Personal protection

    Safety glasses, good ventilation.

    Safety phrases
    (The meaning of any safety phrases which appear in this section is given here.)
    S23 S26 S36 S37 S45 S53.

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This information was last updated on February 25, 2005. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. We have not verified this information, and cannot guarantee that it is up-to-date.