Ethacrynic acid

MERCK & CO INC MERCK-SHARP & DOHME DIV -- SODIUM EDECRIN (INTRAVENOUS INJECTION) -- 6505-00F051952
=====================  Product Identification  =====================

Product ID:SODIUM EDECRIN (INTRAVENOUS INJECTION)
MSDS Date:10/18/1990
FSC:6505
NIIN:00F051952
MSDS Number: CCGBR
=== Responsible Party ===
Company Name:MERCK & CO INC MERCK-SHARP & DOHME DIV
Address:4 SUMNEYTOWN PIKE
City:WEST POINT
State:PA
ZIP:19486-5000
Country:US
Info Phone Num:800-637-2579
Emergency Phone Num:800-637-2579
Preparer's Name:E SARGENT
CAGE:GO622
=== Contractor Identification ===
Company Name:MERCK & CO INC MERCK-SHARP & DOHME DIV
Address:4 SUMNEYTOWN PIKE
City:WEST POINT
State:PA
ZIP:19486-5000
Country:US
Phone:800-637-2579
CAGE:GO622
Company Name:MERCK-SHARP AND DOHME DIV OF MERCK AND CO INC
Address:SUMNEYTOWN PIKE
Box:City:WEST POINT
State:PA
ZIP:19486
Country:US
Phone:215-540-8629
CAGE:06990

=============  Composition/Information on Ingredients  =============

Ingred Name:EDECRIN SODIUM, ETHACRYNATE SODIUM
CAS:6500-81-8
Fraction by Wt: 5%

=====================  Hazards Identification  =====================

Routes of Entry: Inhalation:YES  Skin:NO  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:EYES: OCULAR IRRITANT. SKIN:
    ETHACRYNATE SODIUM CAN CAUSE DERMATITIS. INHALATION: ETHACRYNATE
    SODIUM IS IRRITATING TO THE UPPER RESPIRATORY TRACT. OVERDOSAGE MAY
    LEAD TO EXCESSIVE DIURESIS W/ELECTROLY TE DEPLETION.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION, DEHYDRATION.

=======================  First Aid Measures  =======================

First Aid:EYES: FLUSH W/PLENTY OF WATER. SKIN: WASH HANDS. INHALATION:
    REMOVE TO FRESH AIR. GIVE OXYGEN/CPR IF NEEDED. INGESTION: DECISION
    TO INDUCE EMESIS IS DEPENDENT UPON AMOUNT INGESTED. TREATMENT IS
    SYMPTO MATIC & SUPPORTIVE. OBTAIN MEDICAL ATTENTION IN ALL CASES.
    NOTES TO PHYSICIAN: IF OVERDOSAGE, CORRECT DEHYDRATION, ELECTROLYTE
    IMBALANCE, HEPATIC COMA & HYPOTENSION BY ESTABLISHED PROCEDURES.

=====================  Fire Fighting Measures  =====================

Fire Fighting Procedures:NONE

==================  Accidental Release Measures  ==================

Spill Release Procedures:CONTACT EMERGENCY RESPONSE PERSONNEL. KEEP
    PERSONS AWAY. IF UNAVAILABLE, VACUUM, SHOVEL/SWEEP UP MATERIAL &
    PLACE IN AN APPROPRIATE CONTAINER FOR DISPOSAL. USE SUITABLE
    PROTECTIVE EQUIPMENT. FOLLOW FI RE PREVENTION PROCEDURES.

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE IN COOL DRY PLACE.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NOT REQUIRED.
Ventilation:NONE REQUIRED
Protective Gloves:IMPERVIOUS
Eye Protection:NOT REQUIRED
Other Protective Equipment:WORN UNIFORM.
Supplemental Safety and Health

==================  Physical/Chemical Properties  ==================

Solubility in Water:APPRECIABLE
Appearance and Odor:DRY WHITE POWDER; ODORLESS
Percent Volatiles by Volume:NONE

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
LITHIUM
Stability Condition to Avoid:NONE

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSE OF/TREAT ALL SPILL RESIDUES IAW/FEDERAL,
    STATE & LOCAL REGULATIONS. AVOID CONTACT OF SPILLED MATERIALS &
    RUNOFF W/SOIL & SURFACE WATERWAYS.

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 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
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 particular situation.