Lopirin

• Angiotensin-Converting Enzyme Inhibitors
• Antihypertensive Agents
• ATC:C09AA01

• Acediur
• Aceplus
• Acepress
• Acepril
• Alopresin
• Apopril
• Capoten
• Capozide
• Captolane
• Captopril [Usan:Ban:Inn:Jan]
• Captoprilum [Inn-Latin]
• Captopryl
• Captoril
• Cesplon
• Dilabar
• Garranil
• Hipertil
• Hypertil
• L-Captopril
• Lopirin
• Lopirin [Switzerland]
• Lopril
• Tenosbon
• Tensobon
• Tensoprel

No information avaliable

C₉H₁₅NO₃S

http://www.rxlist.com/cgi/generic/captop.htm

Lopirin MSDS

DW Cushman, US Pat. 4,046,889 (1977)

217.286 g/mol

106^oC

Solubile

Solid

0.546

Compressa (12,5 mg, 25 mg, 50 mg o 100 mg)

Per il trattamento dell'ipertensione. Può essere usato da solo o in combinazione con diuretici tiazidici.

Captopril, un inibitore dell'enzima di conversione dell'angiotensina (ACE), è usato per trattare l'ipertensione, insufficienza cardiaca congestizia, e sindromi renali come la nefropatia diabetica e la sclerodermia. Gli effetti negativi e limitazioni di farmacocinetica di captopril stimolato l'enalapril e il successivo sviluppo ACE-inibitori.

75% senza cibo (la presenza di cibo nel tratto gastrointestinale riduce l'assorbimento di circa il 30 al 40 per cento).

Sintomi di sovradosaggio comprendono coma, letargia, ipotensione, lentezza, e lo stomaco e irritazione intestinale e iperattività.

Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

Patients should be informed that captopril should be taken one hour before meals.

Gli esseri umani e altri mammiferi