Isordil Tembids
Categoria
Isordil Tembids Marchi, Isordil Tembids Analoghi
- Cardio 10
- Cardis
- Carvanil
- Carvasin
- Cedocard
- Claodical
- Cornilat
- Coronex
- Corosorbide
- Dianhydrosorbitol 2,5-dinitrate
- Difutrat
- Dilatrate
- Dilatrate-SR
- Dinitrosorbide
- Emoper
- Flindix
- Harrical
- IBD 20
- ISD
- ISDN
- Ismotic
- Iso-Bid
- Isochron
- Isoket
- Isorbid;
- Isordil
- Isordil Tembids
- Isosorbide dinitrate(USAN)
- Isostat
- Isotrate
- Korodil
- Lomilan
- Maycor
- Myorexon
- Nitrosorbid
- Nitrosorbide
- Nitrosorbon
- Nosim
- Resoidan
- Rifloc Retard
- Rigedal
- Sorbangil
- Sorbide T.D.
- Sorbide nitrate
- Sorbide, dinitrate
- Sorbidilat
- Sorbidnitrate
- Sorbislo
- Sorbitrate
- Sorbonit
- Sorquad
- Tinidil
- Titradose
- Vascardin
- Vasodilat
- Vasorbate
- Xanyl
Isordil Tembids Marchi miscela
Isordil Tembids Formula chimica
C6H8N2O8
Isordil Tembids RX link
http://www.rxlist.com/cgi/generic2/isodinit.htm
Isordil Tembids FDA foglio
Isordil Tembids DMS (foglio di materiale di sicurezza)
Isordil Tembids Sintesi di riferimento
Goldberg, Acta Physiol. Scand.15, 173 (1948)
Isordil Tembids Peso molecolare
236.136 g/mol
Isordil Tembids Temperatura di fusione
70 oC
Isordil Tembids H2O Solubilita
1,089 mg / ml
Isordil Tembids Stato
Solid
Isordil Tembids LogP
-0.53
Isordil Tembids Forme di dosaggio
Orale
Isordil Tembids Indicazione
Per la prevenzione di angina pectoris a causa di malattia coronarica.
Isordil Tembids Farmacologia
Dinitrato è un moderato a lunga durata d'azione nitrati organici orale usato per il sollievo e la gestione profilattico di angina pectoris. Si rilassa la muscolatura liscia vascolare e conseguente dilatazione delle arterie periferiche e delle vene, soprattutto il secondo. Dilatazione delle vene promuove la messa in comune periferico di sangue e diminuisce il ritorno venoso al cuore, riducendo così ventricolare sinistra telediastolica pressione e pressione polmonare capillare (precarico). Rilassamento arteriolare riduce le resistenze vascolari sistemiche, la pressione arteriosa sistolica e pressione arteriosa media.
Isordil Tembids Assorbimento
L'assorbimento di dinitrato dopo somministrazione orale è quasi completa, ma la biodisponibilità è molto variabile (10% al 90%), con ampio metabolismo di primo passaggio nel fegato. La biodisponibilità media di dinitrato è di circa il 25%.
Isordil Tembids Tossicita
Sintomi di sovradosaggio includono riduzione della gittata cardiaca e ipotensione.
Isordil Tembids Informazioni paziente
PATIENT INFORMATION
Patients should be told that the anti-anginal efficacy of isosorbide dinitrate is strongly related
to its dosing regimen, so the prescribed schedule of dosing should be followed carefully. In
particular, daily headaches sometimes accompany treatment with isosorbide dinitrate. In patients
who get these headaches, the headaches are a marker of the activity of the drug. Patients should
resist the temptation to avoid headaches by altering the schedule of their treatment with isosorbide
dinitrate, since loss of headache may be associated with simultaneous loss of anti-anginal efficacy.
Aspirin and/or acetaminophen, on the other hand, often successfully relieve isosorbide dinitrate-
induced headaches with no deleterious effect an isosorbide dinitrate's anti-anginal efficacy.
Treatment with isosorbide dinitrate may be associated with lightheadedness on standing, especially
just after rising from a recumbent or seated position. This effect may be more frequent in patients
who have also consumed alcohol
Patients should be told that the anti-anginal efficacy of isosorbide dinitrate is strongly related
to its dosing regimen, so the prescribed schedule of dosing should be followed carefully. In
particular, daily headaches sometimes accompany treatment with isosorbide dinitrate. In patients
who get these headaches, the headaches are a marker of the activity of the drug. Patients should
resist the temptation to avoid headaches by altering the schedule of their treatment with isosorbide
dinitrate, since loss of headache may be associated with simultaneous loss of anti-anginal efficacy.
Aspirin and/or acetaminophen, on the other hand, often successfully relieve isosorbide dinitrate-
induced headaches with no deleterious effect an isosorbide dinitrate's anti-anginal efficacy.
Treatment with isosorbide dinitrate may be associated with lightheadedness on standing, especially
just after rising from a recumbent or seated position. This effect may be more frequent in patients
who have also consumed alcohol
Isordil Tembids Atto interessato organismi
Gli esseri umani e altri mammiferi
