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  • Allergan 211 Formula chimica

    C9H11IN2O5

    Allergan 211 RX link

    No information avaliable

    Allergan 211 FDA foglio

    Allergan 211 DMS (foglio di materiale di sicurezza)

    http://www.sciencelab.com/xMSDS-Idoxuridine-9924347

    Allergan 211 Sintesi di riferimento

    Prusoff, et al. Biochim Biophys Acta 32, 295 (1959)

    Allergan 211 Peso molecolare

    354.099 g/mol

    Allergan 211 Temperatura di fusione

    164-166oC

    Allergan 211 H2O Solubilita

    <0,01 g/100 ml

    Allergan 211 Stato

    Solid

    Allergan 211 LogP

    -0.253

    Allergan 211 Forme di dosaggio

    Gocce oftalmiche; pomata oftalmica

    Allergan 211 Indicazione

    Per l'uso in cheratocongiuntivite e cheratite causata da virus herpes simplex.

    Allergan 211 Farmacologia

    In idoxuridina struttura chimica si avvicina molto la configurazione di timidina, uno dei quattro elementi costitutivi del DNA (materiale genetico del virus Herpes). Di conseguenza, è in grado idoxuridina per sostituire timidina nel passaggio enzimatico di replicazione virale o di "crescita". La conseguente produzione di risultati del DNA difettoso in un pseudostructure che non possono infettare e distruggere i tessuti. In breve, la pre- svuotare un elemento vitale nel materiale genetico del virus Herpes simplex, Herplex-D soluzione topica distrugge la capacità infettiva e distruttiva del materiale virale. Il virus infetta cella può essere attaccato solo durante il periodo della sintesi del DNA attiva. Ciò si verifica durante lo sviluppo iniziale del Herpes simplex lesione, ma in tempi diversi in celle diverse. Quindi, idealmente, , L'area interessata deve rimanere saturato con l'agente antivirale.

    Allergan 211 Assorbimento

    L'assorbimento sistemico è improbabile che la somministrazione oculare, anche quando le secrezioni naso-lacrimale vengono ingerite, dal momento che si sta rapidamente vidarabina deaminati nel tratto gastrointestinale.

    Allergan 211 Tossicita

    Ipersensibilità o maggiore sensibilità degli occhi alla luce. LD50 = 3080 mg / kg (per via orale nei topi).

    Allergan 211 Informazioni paziente

    Description
    Idoxuridine (eye-dox-YOOR-i-deen) belongs to the family of medicines called antivirals.
    Idoxuridine is used to treat virus infections of the eye.

    Idoxuridine is available only with your doctor's prescription, in the following dosage forms:

    Ophthalmic
    Ophthalmic ointment (U.S. and Canada)
    Ophthalmic solution (eye drops) (U.S. and Canada)

    Proper Use of This Medicine
    For patients using the eye drop form of idoxuridine:

    The bottle is only partially full to provide proper drop control.
    To use:
    First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to
    form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the
    eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.

    If you think you did not get the drop of medicine into your eye properly, use another drop.
    To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface
    (including the eye). Also, keep the container tightly closed.

    For patients using the eye ointment form of idoxuridine:

    To use:
    First, wash your hands. Then pull the lower eyelid away from the eye to form a pouch. Squeeze a
    thin strip of ointment into the pouch. A 1-cm (approximately -inch) strip of ointment is usually
    enough unless otherwise directed by your doctor. Gently close the eyes and keep them closed for 1
    or 2 minutes to allow the medicine to come into contact with the infection.
    To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface
    (including the eye). After using idoxuridine eye ointment, wipe the tip of the ointment tube with
    a clean tissue and keep the tube tightly closed.

    Do not use this medicine more often or for a longer time than your doctor ordered. To do so may
    cause problems in the eyes. If you have any questions about this, check with your doctor.

    To help clear up your infection completely, keep using this medicine for the full time of treatment,
    even though your symptoms may have disappeared. Do not miss any doses.

    Dosing - The dose of idoxuridine will be different for different patients. Follow your doctor's orders
    or the directions on the label. The following information includes only the average doses of idoxuridine.
    If your dose is different, do not change it unless your doctor tells you to do so.

    The number of doses you use each day, the time allowed between doses, and the length of time you use the
    medicine depend on the medical problem for which you are using idoxuridine.

    For virus infections of the eye:
    For eye ointment dosage form:
    Adults and childrenUse every four hours during the day (five times a day).
    For eye solution (eye drops) dosage form:
    Adults and childrenUse every hour during the day and every two hours during the night. After the eye
    condition gets better, use every two hours during the day and every four hours during the night.

    Missed dose - If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost
    time for your next dose, skip the missed dose and go back to your regular dosing schedule.

    Storage - To store this medicine:

    Keep out of the reach of children.
    Store in the refrigerator or in a cool place because heat will cause this medicine to break down. However,
    keep the medicine from freezing. Follow the directions on the label.
    Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of
    the reach of children.

    Allergan 211 Atto interessato organismi

    Herpes simplex virus