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Zonisamide Nombres de marca, Zonisamide Analogos

Zonisamide Marca los nombres de mezcla

  • No information avaliable
  • Zonisamide Formula quimica

    C8H8N2O3S

    Zonisamide RX enlace

    http://www.rxlist.com/cgi/generic3/zonisamide.htm

    Zonisamide FDA hoja

    Zonisamide FDA

    Zonisamide MSDS (hoja de seguridad de materiales)

    Zonisamide MSDS

    Zonisamide Sintesis de referencia

    No hay información disponible

    Zonisamide Peso molecular

    212.227 g/mol

    Zonisamide Punto de fusion

    161-163 oC

    Zonisamide H2O Solubilidad

    0,8 mg / ml

    Zonisamide Estado

    Solid

    Zonisamide LogP

    0.87

    Zonisamide Formas de dosificacion

    Cápsula (100 mg); Tablet

    Zonisamide Indicacion

    Para su uso como tratamiento adyuvante de crisis parciales en adultos con epilepsia.

    Zonisamide Farmacologia

    La zonisamida es un fármaco anticonvulsivo química clasificada como una sulfonamida y no relacionada con agentes anticonvulsivos otros. El mecanismo exacto por el que la zonisamida ejerce su efecto anticonvulsivante se desconoce, aunque se cree que la droga bloquea los canales de sodio, que conduce a la supresión de hipersincronización neuronal (es decir, convulsiones). Asimismo zonisamida también se ha comprobado que no potencian syanptic la actividad de GABA (ácido gamma amino butírico).

    Zonisamide Absorcion

    Tipo de interés variable, pero relativamente rápida de absorción con un tiempo de concentración pico de 02.08 a 03.09 horas. Los alimentos no tienen efecto sobre la biodisponibilidad de la zonisamida.

    Zonisamide Toxicidad

    Los síntomas de sobredosis incluyen respiración disminuida, pérdida de conciencia, presión arterial baja y pulso lento.

    Zonisamide Informacion de Pacientes

    LEAFLET

    Questions and Answers about ZONEGRAN® (zonisamide) capsules

    What is the most important information I should know about ZONEGRAN?

    Some people taking ZONEGRAN (ZON-uh-gran) can get serious reactions. If you get any of the following symptoms, call your doctor right away:

    * Rash (may be a sign of a dangerous condition)

    * Fever, sore throat, sores in your mouth, or bruising easily (may be signs of a blood problem)

    * Sudden back pain, abdominal (stomach area) pain, pain when urinating, bloody or dark urine (may be signs of a kidney stone)

    * Decreased sweating or a rise in body temperature (especially in patients under 17 years old)

    * Depression

    * Thoughts that are unusual for you

    * Speech or language problems

    * Severe muscle pain and/or weakness

    ZONEGRAN can cause drowsiness and coordination problems.

    Do not drive or operate dangerous machinery until you know how ZONEGRAN affects you.

    What Is ZONEGRAN?

    ZONEGRAN is a medicine to treat partial seizures in adults. It is taken with other seizure medicines to help control your seizures.

    Who should not take ZONEGRAN?

    Talk to your doctor first before stopping ZONEGRAN.

    Tell your doctor if you are allergic to sulfa drugs. Do not take ZONEGRAN if you are allergic to any sulfa drugs (for example, BactrimTM or Septra®) or ZONEGRAN.

    How should I take ZONEGRAN?

    Be sure to follow your doctorís directions. Starting a new medicine can be confusing. If you have any questions, call your doctor.

    Start with one ZONEGRAN capsule each day (100 mg). Swallow the capsule whole. Do not bite into or break the capsule. You may take this medicine with or without food.

    After a week or so, your doctor may increase your dose of ZONEGRAN. This may occur more than once. It is done to get the best control for your seizures. Take only the number of ZONEGRAN capsules you were told to take.

    Talk to your doctor about what to do if you miss a dose.

    If you think you have overdosed on your medicine, call your local poison control center or emergency room right away.

    Drink 6-8 glasses of water a day. This may help prevent kidney stones.

    Talk to your doctor before stopping ZONEGRAN or any other seizure medicine. Stopping a seizure medicine all at once can cause status epilepticus, a serious problem.

    What shoud I avoid while taking ZONEGRAN?

    ZONEGRAN may make you drowsy. Do not drive a car or operate complex machinery until you know how ZONEGRAN may affect you.

    Tell your doctor about any other medicines you may be taking, including non-prescription medicines.

    Tell your doctor right away if you are pregnant or plan to become pregnant. You and your doctor can decide if the benefits of taking ZONEGRAN outweigh the risks. ZONEGRAN may cause birth defects.

    It is not known whether ZONEGRAN is passed through breast milk to the baby. Before taking ZONEGRAN, tell your doctor if you are nursing or planning to nurse your baby.

    What are the possible or reasonably likely side effects of ZONEGRAN?

    The most common side effects are drowsiness, loss of appetite, dizziness, headache, nausea, agitation, and irritability. These side effects could occur at any time, but most often occur in the first 4 weeks.

    Contact your doctor right away if:

    * you develop skin rash

    * your seizures worsen

    * you develop signs of kidney stones (sudden back pain, abdominal pain, blood in your urine)

    * you develop signs of a blood problem (fever, sore throat, sores in your mouth, or bruising easily)

    * you get depressed

    * you start having thoughts that are unusual for you

    * you are very drowsy, have difficulty concentrating, or have coordination problems

    * you develop speech or language problems

    Other information about ZONEGRAN:

    Medicines are sometimes prescribed for purposes other than those listed in a patient leaflet. Use ZONEGRAN only for the reason your doctor told you. Do not use it for another reason. Do not share your ZONEGRAN with others.

    This is a summary of information about ZONEGRAN. Call your healthcare professional with any questions. Your doctor or pharmacist can give you the complete information about ZONEGRAN that is written for health professionals. You can also get information about ZONEGRAN at www.elan.com. You can get information and help from the Epilepsy Foundation at 800-EFA-1000 or www.efa.org.

    Distributed by: Elan Biopharmaceuticals, a business unit of Elan Pharmaceuticals, Inc.

    San Diego, CA 92121, ZONEGRAN is a trademark licensed exclusively to Elan Pharmaceuticals, Inc., All other product names may be trademarks of the respective companies with which they are associated., © 2000 Elan Pharmaceuticals, Inc.

    Zonisamide Organismos afectados

    Humanos y otros mamíferos