Benazepril Hydrochloride en es it fr

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Benazepril Hydrochloride Nombres de marca, Benazepril Hydrochloride Analogos

Benazepril Hydrochloride Marca los nombres de mezcla

  • Lotensin HCT (Benazepril Hydrochloride + Hydrochlorothiazide)
  • Lotrel (Benazepril Hydrochloride + Amlodipine Besylate)
  • Benazepril Hydrochloride Formula quimica

    C24H28N2O5

    Benazepril Hydrochloride RX enlace

    http://www.rxlist.com/cgi/generic/benaz.htm

    Benazepril Hydrochloride FDA hoja

    Benazepril_Hydrochloride FDA

    Benazepril Hydrochloride MSDS (hoja de seguridad de materiales)

    Benazepril_Hydrochloride MSDS

    Benazepril Hydrochloride Sintesis de referencia

    USpat.4, 410.520 (1983)

    Benazepril Hydrochloride Peso molecular

    424.49 g/mol

    Benazepril Hydrochloride Punto de fusion

    148-149 oC

    Benazepril Hydrochloride H2O Solubilidad

    2,229 mg / L

    Benazepril Hydrochloride Estado

    Solid

    Benazepril Hydrochloride LogP

    3.217

    Benazepril Hydrochloride Formas de dosificacion

    Comprimido (5 mg, 10 mg, 20 mg, 40 mg)

    Benazepril Hydrochloride Indicacion

    Para el tratamiento de la hipertensión. Se puede utilizar solo o en combinación con diuréticos tiazídicos.

    Benazepril Hydrochloride Farmacologia

    Benazepril, un inhibidor de la enzima convertidora de angiotensina (ECA), es un profármaco que, cuando se hidroliza por estarases a su benazeprilato activo, se utiliza para tratar la hipertensión y la insuficiencia cardiaca, para reducir la proteinuria y la enfermedad renal en pacientes con nefropatías, y para evitar accidente cerebrovascular, infarto de miocardio y muerte cardíaca en pacientes de alto riesgo. Benazepril y benazeprilato inhibir la enzima convertidora de angiotensina (ACE) en seres humanos y animales. La ECA es una peptidil dipeptidasa que cataliza la conversión de angiotensina I en la sustancia vasoconstrictora de la angiotensina II. La angiotensina II también estimula la aldosterona la secreción de la corteza suprarrenal.

    Benazepril Hydrochloride Absorcion

    Pico en el plasma dentro de 0.5-1.0 horas. El grado de absorción es al menos el 37%, determinado mediante recuperación urinaria y no es significativamente influenciado por la presencia de alimentos en el tracto gastrointestinal.

    Benazepril Hydrochloride Toxicidad

    Los síntomas de sobredosis incluyen inflamación de la cara, boca, manos o pies, dificultad para tragar o respirar (de repente), ronquera, fiebre y escalofríos.

    Benazepril Hydrochloride Informacion de Pacientes

    Pregnancy

    Female patients of childbearing age should be told about the consequences of second- and third-trimester exposure to ACE inhibitors, and they should also be told that these consequences do not appear to have resulted from intrauterine ACE inhibitor exposure that has been limited to the first trimester. These patients should be asked to report pregnancies to their physicians as soon as possible.

    Angioedema

    Angioedema, including laryngeal edema, can occur at any time with treatment with ACE inhibitors. Patients should be so advised and told to report immediately any signs or symptoms suggesting angioedema (swelling of face, eyes, lips, or tongue, or difficulty in breathing) and to take no more drug until they have consulted with the prescribing physician.

    Symptomatic Hypotension

    Patients should be cautioned that lightheadedness can occur, especially during the first days of therapy, and it should be reported to the prescribing physician. Patients should be told that if syncope occurs, Lotensin should be discontinued until the prescribing physician has been consulted.

    All patients should be cautioned that inadequate fluid intake or excessive perspiration, diarrhea, or vomiting can lead to an excessive fall in blood pressure, with the same consequences of lightheadedness and possible syncope.

    Hyperkalemia

    Patients should be told not to use potassium supplements or salt substitutes containing potassium without consulting the prescribing physician.

    Neutropenia

    Patients should be told to promptly report any indication of infection (e.g., sore throat, fever), which could be a sign of neutropenia.

    Benazepril Hydrochloride Organismos afectados

    Humanos y otros mamíferos