(+-)-Isradipine en es it fr

Categoria

(+-)-Isradipine Nombres de marca, (+-)-Isradipine Analogos

(+-)-Isradipine Marca los nombres de mezcla

  • No information avaliable
  • (+-)-Isradipine Formula quimica

    C19H21N3O5

    (+-)-Isradipine RX enlace

    http://www.rxlist.com/cgi/generic2/israd.htm

    (+-)-Isradipine FDA hoja

    (+-)-Isradipine MSDS (hoja de seguridad de materiales)

    (+-)-Isradipine MSDS

    (+-)-Isradipine Sintesis de referencia

    P. Neumann, EE.UU. Pat. 4,466,972 (1984)

    (+-)-Isradipine Peso molecular

    371.387 g/mol

    (+-)-Isradipine Punto de fusion

    168-170 oC

    (+-)-Isradipine H2O Solubilidad

    Prácticamente insoluble (<10 mg / L a 37 ° C)

    (+-)-Isradipine Estado

    Solid

    (+-)-Isradipine LogP

    2.901

    (+-)-Isradipine Formas de dosificacion

    Cápsulas (2,5 mg o 5 mg)

    (+-)-Isradipine Indicacion

    Para el manejo de la hipertensión. Se puede utilizar solo o junto con los diuréticos tipo tiazida.

    (+-)-Isradipine Farmacologia

    Isradipino, el más potente del canal del calcio agente de bloqueo de la clase dihidropiridina, es similar a la nifedipina, amlodipina, y felodipino. Se une a los canales de calcio con una alta afinidad y especificidad e inhibe el flujo de calcio en el músculo cardiaco y liso. Los efectos observados en los experimentos de mecánica in vitro y estudiado en los animales intactos y el hombre son compatibles con este mecanismo de acción y son típicos de la clase.

    (+-)-Isradipine Absorcion

    Isradipina es de 90% -95% es absorbido y es sujeto a un amplio metabolismo de primer paso, resultando en una biodisponibilidad de aproximadamente el 15% -24%.

    (+-)-Isradipine Toxicidad

    Los síntomas de sobredosis incluyen letargo, taquicardia sinusal e hipotensión transitoria. Letalidad significativa se observó en los ratones que recibieron dosis orales de más de 200 mg / kg y conejos que recibieron aproximadamente 50 mg / kg de isradipina. Las ratas toleraron dosis de más de 2000 mg / kg sin efectos sobre la supervivencia.

    (+-)-Isradipine Informacion de Pacientes

    Description
    --------------------------------------------------------------------------------

    For those patients who have high blood pressure, and is sometime used to treat angina
    (chest pains).

    General Information
    --------------------------------------------------------------------------------

    This information is for educational purposes only. Not every known side effect, adverse
    effect, or drug interaction is in this database. If you have questions about your medicines,
    talk to your healthcare provider.

    Proper use of this medicine
    --------------------------------------------------------------------------------

    Take this medicine exactly as directed. This medicine is normally taken once daily. It is
    taken orally and may be taken with or without food. The extended-release tablet and capsule
    should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or
    capsule.


    Missed Dose
    --------------------------------------------------------------------------------

    Take your next dose as soon as you remember. If it is time for your next dose, skip the
    missed dose and go back to your regular schedule. Do not double doses.


    Storage
    --------------------------------------------------------------------------------

    Keep this medication in the container it came in, tightly closed, and out of reach of
    children. Store it at room temperature and away from excess heat and moisture. Throw away
    any medication that is outdated or no longer needed.


    Possible Side Effects
    --------------------------------------------------------------------------------

    If you experience other bothersome side effects, contact your health care provider.
    Some common side effects reported with this medicine include:
    nausea
    dizziness
    headache
    swelling


    Warnings/Precautions
    --------------------------------------------------------------------------------

    Do not stop suddenly stop this medicine without talking to your doctor.
    This medicine can cause dizziness. Use caution when operating a motor vehicle.


    Overdose
    --------------------------------------------------------------------------------

    Seek medical attention immediately. For non emergencies, contact your local or regional
    poison control center


    Drug Interactions
    --------------------------------------------------------------------------------

    Tell your doctor and pharmacist about all other medicines that you are taking, including
    non-prescription medicines, nutritional supplements, or herbal products.


    Pregnancy/Nursing
    --------------------------------------------------------------------------------

    If you suspect that you may be pregnant, talk to your doctor. There are no clear answers,
    but animal studies suggest caution during pregnancy, and use should only be when risks are
    outweighed by possible benefits. For nursing mothers, it is not known if amlodipine is
    excreted in breast milk, so caution is recommended.


    More Information
    --------------------------------------------------------------------------------

    For more information about this medicine, talk to your healthcare provider.

    (+-)-Isradipine Organismos afectados

    Humanos y otros mamíferos