cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) en es it fr

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Brand names, cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Analogs

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Brand Names Mixture

  • No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Chemical_Formula

C6H12N2O4Pt2

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) RX_link

http://www.rxlist.com/cgi/generic3/carboplat.htm

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) fda sheet

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) FDA

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) msds (material safety sheet)

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) MSDS

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Synthesis Reference

No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Molecular Weight

371.249 g/mol

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Melting Point

No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) H2O Solubility

No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) State

Solid

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) LogP

No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Dosage Forms

Solution

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Indication

For the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of PARAPLATIN and cyclophosphamide.

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Pharmacology

Carboplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Absorption

No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) side effects and Toxicity

Toxic by ingestion. May be create toxic effect through inhalation or skin contact. May cause reproductive defects. May act as a sensitizer.

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Patient Information

No information avaliable

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) Organisms Affected

Humans and other mammals