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antiCD11 alpha Brand names, antiCD11 alpha Analogs

antiCD11 alpha Brand Names Mixture

  • No information avaliable

antiCD11 alpha Chemical_Formula

No information avaliable

antiCD11 alpha RX_link

http://www.rxlist.com/cgi/generic3/raptiva.htm

antiCD11 alpha fda sheet

antiCD11 alpha msds (material safety sheet)

antiCD11 alpha Synthesis Reference

sequence listed in Werther WA, Gonzalez TN, O'Connor SJ, McCabe S, Chan B, Hotaling T, Champe M, Fox JA, Jardieu PM, Berman PW, Presta LG. Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J Immunol. 1996 Dec 1;157(11):4986-95

antiCD11 alpha Molecular Weight

No information avaliable

antiCD11 alpha Melting Point

61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

antiCD11 alpha H2O Solubility

No information avaliable

antiCD11 alpha State

Liquid

antiCD11 alpha LogP

No information avaliable

antiCD11 alpha Dosage Forms

Solution (Subcutaneous Injection)

antiCD11 alpha Indication

For treatment of psoriasis

antiCD11 alpha Pharmacology

Lymphocyte activation and trafficking to skin play a role in the pathophysiology of chronic plaque psoriasis. In psoriatic skin, ICAM-1 cell surface expression is upregulated on endothelium and keratinocytes. Raptiva inhibits the binding of LFA-1 to the intercellular adhesion molecule-1 (ICAM-1), thereby inhibiting the adhesion of leukocytes to other cell types.

antiCD11 alpha Absorption

No information avaliable

antiCD11 alpha side effects and Toxicity

No information avaliable

antiCD11 alpha Patient Information

BIOD00074.html

antiCD11 alpha Organisms Affected

Humans and other mammals