Zymase (Organon)

• Enzyme replacement

• 1,4-alpha-D- glucan glucanohydrolase
• PA
• Pancreatic alpha-amylase precursor
• Cotazym (Organon)
• Ku-Zyme (Koichi)
• Pancrease (Ortho-McNeil)
• Ultrase (Axcan Scandipharm)
• Zymase (Organon)

• No information avaliable

C₅₈₅₀H₈₉₀₂N₁₆₀₆O₁₇₃₉S₄₉

http://www.rxlist.com/cgi/generic2/pancrel.htm

No information avaliable

131125.6

48-50 ^oC (Vinogradov, A.A. et al., Protein Eng. 14:683-689 (2001)).

No information avaliable

Liquid

No information avaliable

Tablet

For treatment of cystic fibrosis, chronic pancreatitis, pancreatic duct blockage

Used in the treatment of cystic fibrosis or pancreatic dysfunction, pancrelipase helps improve fat digestion in the small intestine. Specifically, the lipase, protease and amylase components break down fat, protein, and starches, respectively, in the small intestine. Lipase hydrolyzes fats into glycerol and fatty acids. Protease converts proteins into proteoses and derived substances, while amylase converts starches into dextrins and sugars. Pancreatic enzymes are used to correct maldigestion, malabsorption and pain associated with pancreatic insufficiency. The major maldigestion/malabsorption problems arise from incomplete fat digestion. Exogenous pancrelipase reduces the amount of nitrogen and fat excreted in the stool.

No information avaliable

No information avaliable

No information avaliable

Humans and other mammals