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ZK5 Brand names, ZK5 Analogs

ZK5 Brand Names Mixture

  • No information avaliable

ZK5 Chemical_Formula

C21H29FO5

ZK5 RX_link

http://www.rxlist.com/cgi/generic/fludro.htm

ZK5 fda sheet

ZK5 msds (material safety sheet)

ZK5 MSDS

ZK5 Synthesis Reference

No information avaliable

ZK5 Molecular Weight

380.45 g/mol

ZK5 Melting Point

No information avaliable

ZK5 H2O Solubility

140 mg/L

ZK5 State

Solid

ZK5 LogP

1.49

ZK5 Dosage Forms

Tablet

ZK5 Indication

For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.

ZK5 Pharmacology

Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.

ZK5 Absorption

No information avaliable

ZK5 side effects and Toxicity

Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.

ZK5 Patient Information

ZK5 Organisms Affected

Humans and other mammals