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Vytorin Brand names, Vytorin Analogs

Vytorin Brand Names Mixture

  • No information avaliable

Vytorin Chemical_Formula

C25H38O5

Vytorin RX_link

http://www.rxlist.com/cgi/generic/simva.htm

Vytorin fda sheet

Vytorin FDA

Vytorin msds (material safety sheet)

Vytorin Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Vytorin Molecular Weight

418.566 g/mol

Vytorin Melting Point

135-138oC

Vytorin H2O Solubility

0.76 mg/L

Vytorin State

Solid

Vytorin LogP

4.937

Vytorin Dosage Forms

Tablet (oral)

Vytorin Indication

For the treatment of hypercholesterolemia.

Vytorin Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Vytorin Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Vytorin side effects and Toxicity

No information avaliable

Vytorin Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Vytorin Organisms Affected

Humans and other mammals