Vibramycin
Vibramycin Brand names, Vibramycin Analogs
Vibramycin Brand Names Mixture
- No information avaliable
Vibramycin Chemical_Formula
C22H24N2O8
Vibramycin RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Vibramycin fda sheet
Vibramycin msds (material safety sheet)
Vibramycin Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Vibramycin Molecular Weight
444.435 g/mol
Vibramycin Melting Point
201 oC
Vibramycin H2O Solubility
630 mg/L
Vibramycin State
Solid
Vibramycin LogP
-1.219
Vibramycin Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Vibramycin Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Vibramycin Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Vibramycin Absorption
completely absorbed after oral administration
Vibramycin side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Vibramycin Patient Information
Vibramycin Organisms Affected
Enteric bacteria and other eubacteria
