Verapamil

• Vasodilator Agents
• Antiarrhythmic Agents
• Calcium-channel blocking agents
• ATC:C08DA01

• Apo-Verap
• Arpamyl
• Berkatens
• Calan
• Calan SR
• Cardiagutt
• Cardibeltin
• Cordilox
• Covera-HS
• Dignover
• Dilacoran
• Drosteakard
• Geangin
• Iproveratril
• Isoptimo
• Isoptin
• Isoptin SR
• Novo-Veramil
• NU-Verap
• Quasar
• Securon
• Univer
• Vasolan
• Veracim
• Veramex
• Verapamil HCl
• Verapamil [Usan:Ban:Inn]
• Verapamilo [Inn-Spanish]
• Verapamilum [Inn-Latin]
• Veraptin
• Verelan
• Verelan PM
• Verexamil

• Tarka (trandolapril + verapamil hydrochloride)

C₂₇H₃₈N₂O₄

http://www.rxlist.com/cgi/generic/verapsr.htm

Verapamil FDA

Dengel, U.S. Pat. 3,261,859 (1966)

454.602 g/mol

< 25 ^oC

4.47 mg/L

Liquid

5.931

Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)

For the treatment of hypertension and angina.

Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.

90%

LD₅₀=8 mg/kg (i.v. in mice)

Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses may need some adjustment, make sure to have your condition monitored regularly.

Humans and other mammals