Valaciclovir en es it fr

Valaciclovir Brand names, Valaciclovir Analogs

Valaciclovir Brand Names Mixture

  • No information avaliable

Valaciclovir Chemical_Formula


Valaciclovir RX_link

Valaciclovir fda sheet

Valaciclovir FDA

Valaciclovir msds (material safety sheet)

Valaciclovir MSDS

Valaciclovir Synthesis Reference

No information avaliable

Valaciclovir Molecular Weight

324.336 g/mol

Valaciclovir Melting Point

No information avaliable

Valaciclovir H2O Solubility

No information avaliable

Valaciclovir State


Valaciclovir LogP

No information avaliable

Valaciclovir Dosage Forms


Valaciclovir Indication

For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals.

Valaciclovir Pharmacology

Valacyclovir is a prodrug and synthetic purine nucleoside analogue with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is almost completely converted to acyclovir and L-valine. The inhibitory activity of valacyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, which is then converted into acyclovir diphosphate and triphosphate by cellular enzymes. Acyclovir is selectively converted to the active triphosphate form by cells infected with herpes viruses.

Valaciclovir Absorption

After oral administration, valacyclovir hydrochloride is rapidly absorbed from the gastrointestinal tract. The absolute bioavailability of acyclovir after administration of valacyclovir is 54.5% ± 9.1%.

Valaciclovir side effects and Toxicity

Adverse effects of overexposure might include headache and nausea.

Valaciclovir Patient Information

Valaciclovir Organisms Affected

Human herpes virus