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USAN Brand names, USAN Analogs

USAN Brand Names Mixture

  • No information avaliable

USAN Chemical_Formula

C19H16ClNO4

USAN RX_link

http://www.rxlist.com/cgi/generic/indometh.htm

USAN fda sheet

USAN msds (material safety sheet)

USAN MSDS

USAN Synthesis Reference

No information avaliable

USAN Molecular Weight

357.787 g/mol

USAN Melting Point

158 oC

USAN H2O Solubility

0.937 mg/L

USAN State

Solid

USAN LogP

3.655

USAN Dosage Forms

Capsule

USAN Indication

For moderate to severe rheumatoid arthritis including acute flares of chronic disease, ankylosing spondylitis, osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.

USAN Pharmacology

Indomethacin, a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

USAN Absorption

No information avaliable

USAN side effects and Toxicity

No information avaliable

USAN Patient Information

Indomethacin, like other drugs of its class, is not free of side effects. The side effects of these drugs can cause discomfort and rarely, there are more serious side effects, such as gastrointestinal bleeding, which may result in hospitalization and even fatal outcomes. NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) are often essential agents in the management of arthritis, but they also may be commonly employed for conditions which are less serious. Physicians may wish to discuss with their patients the potential risks and likely benefits of NSAID treatment, particularly when the drugs are used for less serious conditions where treatment without NSAIDs may represent an acceptable alternative to both the patient and physician.

USAN Organisms Affected

Humans and other mammals